Periostin drives extracellular matrix degradation, stemness, and chemoresistance by activating the MAPK/ERK signaling pathway in triple-negative breast cancer cells.

Wu, Jinna; Li, Jia; Xu, Huiya; Qiu, Ni; Huang, Xiaojia; Li, Hongsheng

Wu, Jinna; Li, Jia; Xu, Huiya; Qiu, Ni; Huang, Xiaojia; Li, Hongsheng.

Afiliação

Wu J; Department of Breast Oncology Surgery, Affiliated Cancer Hospital & Institute of Guangzhou Medical University, Guangzhou, 510095, China.
Li J; Department of Breast Oncology Surgery, Affiliated Cancer Hospital & Institute of Guangzhou Medical University, Guangzhou, 510095, China.
Xu H; Department of Pathology, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, 510120, China.
Qiu N; Department of Breast Oncology Surgery, Affiliated Cancer Hospital & Institute of Guangzhou Medical University, Guangzhou, 510095, China.
Huang X; Department of Breast Oncology Surgery, Affiliated Cancer Hospital & Institute of Guangzhou Medical University, Guangzhou, 510095, China.
Li H; Department of Breast Oncology Surgery, Affiliated Cancer Hospital & Institute of Guangzhou Medical University, Guangzhou, 510095, China. docli999@163.com.

Lipids Health Dis ; 22(1): 153, 2023 Sep 16.

Article em En | MEDLINE | ID: mdl-37716956

Assuntos

Neoplasias de Mama Triplo Negativas; Humanos; Neoplasias de Mama Triplo Negativas/tratamento farmacológico; Neoplasias de Mama Triplo Negativas/genética; Resistencia a Medicamentos Antineoplásicos/genética; Transdução de Sinais; Sistema de Sinalização das MAP Quinases; Adipócitos; Microambiente Tumoral/genética

Palavras-chave

Adipocytes; MAPK/ERK signaling pathway; Palmitic acid; Periostin; Triplenegative breast cancer

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias de Mama Triplo Negativas Limite: Humans Idioma: En Ano de publicação: 2023 Tipo de documento: Article

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