Asiatic acid protects against pressure overload-induced heart failure in mice by inhibiting mitochondria-dependent apoptosis.

Du, Junjie; Yu, Dongmin; Li, Jinghang; Si, Linjie; Zhu, Dawei; Li, Ben; Gao, Yizhou; Sun, Lifu; Wang, Xufeng; Wang, Xiaowei

Du, Junjie; Yu, Dongmin; Li, Jinghang; Si, Linjie; Zhu, Dawei; Li, Ben; Gao, Yizhou; Sun, Lifu; Wang, Xufeng; Wang, Xiaowei.

Afiliação

Du J; Department of Cardiovascular Surgery, The First Afï¬liated Hospital of Nanjing Medical University, Nanjing, 210029, China. Electronic address: junjie.du@njmu.edu.cn.
Yu D; Department of Cardiovascular Surgery, The First Afï¬liated Hospital of Nanjing Medical University, Nanjing, 210029, China.
Li J; Department of Cardiovascular Surgery, The First Afï¬liated Hospital of Nanjing Medical University, Nanjing, 210029, China.
Si L; Department of Cardiovascular Surgery, The First Afï¬liated Hospital of Nanjing Medical University, Nanjing, 210029, China.
Zhu D; Department of Cardiothoracic Surgery, Sir Run Run Hospital, Nanjing Medical University, Nanjing, 211000, China.
Li B; Department of Cardiovascular Surgery, The First Afï¬liated Hospital of Nanjing Medical University, Nanjing, 210029, China.
Gao Y; Department of Cardiovascular Surgery, The First Afï¬liated Hospital of Nanjing Medical University, Nanjing, 210029, China.
Sun L; Department of Cardiovascular Surgery, The First Afï¬liated Hospital of Nanjing Medical University, Nanjing, 210029, China.
Wang X; Department of Cardiovascular Surgery, The First Afï¬liated Hospital of Nanjing Medical University, Nanjing, 210029, China.
Wang X; Department of Cardiovascular Surgery, The First Afï¬liated Hospital of Nanjing Medical University, Nanjing, 210029, China. Electronic address: wangxiaowei@njmu.edu.cn.

Free Radic Biol Med ; 208: 545-554, 2023 11 01.

Article em En | MEDLINE | ID: mdl-37717794

Assuntos

Insuficiência Cardíaca; Peróxido de Hidrogênio; Camundongos; Ratos; Animais; Peróxido de Hidrogênio/metabolismo; Insuficiência Cardíaca/metabolismo; Apoptose; Miócitos Cardíacos/metabolismo; Estresse Oxidativo; Mitocôndrias/metabolismo; Camundongos Endogâmicos C57BL

Palavras-chave

Apoptosis; Asiatic acid; Cardiomyocyte; Mitochondria; Oxidative stress

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Insuficiência Cardíaca / Peróxido de Hidrogênio Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Ano de publicação: 2023 Tipo de documento: Article

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