[Diagnosis and treatment of Minimal Change Disease in adults-2023]. / Diagnostik und Therapie der Minimal Change Glomerulopathie beim Erwachsenen 2023.
Wien Klin Wochenschr
; 135(Suppl 5): 628-637, 2023 Aug.
Article
em De
| MEDLINE
| ID: mdl-37728648
Minimal change disease is a glomerulopathy that clinically manifests as acute onset nephrotic syndrome. A diagnosis is made by renal biopsy, implying the absence of glomerular lesions on light microscopy but detection of extensive podocyte foot process effacement on electron miscroscopy. Considering the typically excellent response to immunosuppressive measures (especially to glucocorticoids), an autoimmune pathogenesis is assumed. Although general prognosis is overall beneficial, steroid-dependent, steroid-resistant and frequently-relapsing disease courses may complicate the management of these patients and necessitate the use of alternative immunosuppressive treatment strategies. Here, the Austrian Society of Nephrology (ÖGN) provides a consensus on how to best diagnose and manage adult patients with minimal change disease.
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Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Nefrologia
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Nefrose Lipoide
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Síndrome Nefrótica
Tipo de estudo:
Diagnostic_studies
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Guideline
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Prognostic_studies
Limite:
Adult
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Humans
País como assunto:
Europa
Idioma:
De
Ano de publicação:
2023
Tipo de documento:
Article