Cell-specific genome-scale metabolic modeling of SARS-CoV-2-infected lung to identify antiviral enzymes.

Chen, Ke-Lin; Wang, Feng-Sheng

Chen, Ke-Lin; Wang, Feng-Sheng.

Afiliação

Chen KL; Department of Chemical Engineering, National Chung Cheng University, Chiayi, Taiwan.
Wang FS; Department of Chemical Engineering, National Chung Cheng University, Chiayi, Taiwan.

FEBS Open Bio ; 13(12): 2172-2186, 2023 12.

Article em En | MEDLINE | ID: mdl-37734920

Assuntos

COVID-19; SARS-CoV-2; Humanos; SARS-CoV-2/genética; COVID-19/genética; Di-Hidro-Orotato Desidrogenase; Antivirais/farmacologia; Pulmão; Lipídeos

Palavras-chave

antiviral target design; constraint-based model; fuzzy optimization; genome-scale metabolic model; hybrid differential evolution; multilevel optimization

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: SARS-CoV-2 / COVID-19 Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Ano de publicação: 2023 Tipo de documento: Article

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google