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Structure-based design of a single-chain triple-disulfide-stabilized fusion-glycoprotein trimer that elicits high-titer neutralizing responses against human metapneumovirus.
Ou, Li; Chen, Steven J; Teng, I-Ting; Yang, Lijuan; Zhang, Baoshan; Zhou, Tongqing; Biju, Andrea; Cheng, Cheng; Kong, Wing-Pui; Morano, Nicholas C; Stancofski, Erik-Stephane D; Todd, John-Paul; Tsybovsky, Yaroslav; Wang, Shuishu; Zheng, Cheng-Yan; Mascola, John R; Shapiro, Lawrence; Woodward, Ruth A; Buchholz, Ursula J; Kwong, Peter D.
Afiliação
  • Ou L; Vaccine Research Center, National Institutes of Health, Bethesda, Maryland, United States of America.
  • Chen SJ; Vaccine Research Center, National Institutes of Health, Bethesda, Maryland, United States of America.
  • Teng IT; Vaccine Research Center, National Institutes of Health, Bethesda, Maryland, United States of America.
  • Yang L; Laboratory of Infectious Diseases, National Institute of Allergy and Infectious Diseases, Bethesda, Maryland, United States of America.
  • Zhang B; Vaccine Research Center, National Institutes of Health, Bethesda, Maryland, United States of America.
  • Zhou T; Vaccine Research Center, National Institutes of Health, Bethesda, Maryland, United States of America.
  • Biju A; Vaccine Research Center, National Institutes of Health, Bethesda, Maryland, United States of America.
  • Cheng C; Vaccine Research Center, National Institutes of Health, Bethesda, Maryland, United States of America.
  • Kong WP; Vaccine Research Center, National Institutes of Health, Bethesda, Maryland, United States of America.
  • Morano NC; Zuckerman Mind Brain Behavior Institute, Columbia University, New York, New York, United States of America.
  • Stancofski ED; Department of Biochemistry and Molecular Biophysics, Columbia University Vagelos College of Physicians and Surgeons, New York, New York, United States of America.
  • Todd JP; Vaccine Research Center, National Institutes of Health, Bethesda, Maryland, United States of America.
  • Tsybovsky Y; Vaccine Research Center, National Institutes of Health, Bethesda, Maryland, United States of America.
  • Wang S; Electron Microscopy Laboratory, Cancer Research Technology Program, Frederick National Laboratory for Cancer Research, Frederick, Maryland, United States of America.
  • Zheng CY; Vaccine Research Center, National Institutes of Health, Bethesda, Maryland, United States of America.
  • Mascola JR; Vaccine Research Center, National Institutes of Health, Bethesda, Maryland, United States of America.
  • Shapiro L; Vaccine Research Center, National Institutes of Health, Bethesda, Maryland, United States of America.
  • Woodward RA; Zuckerman Mind Brain Behavior Institute, Columbia University, New York, New York, United States of America.
  • Buchholz UJ; Department of Biochemistry and Molecular Biophysics, Columbia University Vagelos College of Physicians and Surgeons, New York, New York, United States of America.
  • Kwong PD; Vaccine Research Center, National Institutes of Health, Bethesda, Maryland, United States of America.
PLoS Pathog ; 19(9): e1011584, 2023 09.
Article em En | MEDLINE | ID: mdl-37738240
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Vírus Sincicial Respiratório Humano / Metapneumovirus Limite: Aged / Animals / Humans Idioma: En Ano de publicação: 2023 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Vírus Sincicial Respiratório Humano / Metapneumovirus Limite: Aged / Animals / Humans Idioma: En Ano de publicação: 2023 Tipo de documento: Article