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Efficacy and safety of subcutaneous spesolimab for the prevention of generalised pustular psoriasis flares (Effisayil 2): an international, multicentre, randomised, placebo-controlled trial.
Morita, Akimichi; Strober, Bruce; Burden, A David; Choon, Siew Eng; Anadkat, Milan J; Marrakchi, Slaheddine; Tsai, Tsen-Fang; Gordon, Kenneth B; Thaçi, Diamant; Zheng, Min; Hu, Na; Haeufel, Thomas; Thoma, Christian; Lebwohl, Mark G.
Afiliação
  • Morita A; Department of Geriatric and Environmental Dermatology, Nagoya City University Graduate School of Medical Sciences, Nagoya, Japan.
  • Strober B; Department of Dermatology, Yale University School of Medicine, New Haven, CT, USA; Central Connecticut Dermatology, Cromwell, CT, USA.
  • Burden AD; School of Infection and Immunity, University of Glasgow, Glasgow, UK.
  • Choon SE; Department of Dermatology, Hospital Sultanah Aminah, and Clinical School Johor Bahru, Monash University Malaysia, Malaysia.
  • Anadkat MJ; Division of Dermatology, Washington University School of Medicine, St Louis, MO, USA.
  • Marrakchi S; Department of Dermatology, Hedi Chaker Hospital, University of Sfax, Sfax, Tunisia.
  • Tsai TF; Department of Dermatology, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei, Taiwan.
  • Gordon KB; Department of Dermatology, Medical College of Wisconsin, Milwaukee, WI, USA.
  • Thaçi D; Comprehensives Center for Inflammation Medicine, University of Lübeck, Lübeck, Germany.
  • Zheng M; Department of Dermatology, Second Affiliated Hospital, Zhejiang University, School of Medicine, Hangzhou, Zhejiang, China.
  • Hu N; Boehringer Ingelheim (China) Investment Co, Shanghai, China.
  • Haeufel T; Boehringer Ingelheim International, Ingelheim, Germany.
  • Thoma C; Boehringer Ingelheim International, Biberach, Germany.
  • Lebwohl MG; Icahn School of Medicine at Mount Sinai, New York, NY, USA. Electronic address: mark.lebwohl@mountsinai.org.
Lancet ; 402(10412): 1541-1551, 2023 10 28.
Article em En | MEDLINE | ID: mdl-37738999

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Psoríase / Qualidade de Vida Tipo de estudo: Clinical_trials / Prognostic_studies Limite: Adolescent / Adult / Aged / Child / Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2023 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Psoríase / Qualidade de Vida Tipo de estudo: Clinical_trials / Prognostic_studies Limite: Adolescent / Adult / Aged / Child / Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2023 Tipo de documento: Article