Advancing small-molecule drug discovery by encoded dual-display technologies.

Lessing, Alice; Petrov, Dimitar; Scheuermann, Jörg.

Afiliação

Lessing A; ETH Zürich, Department of Chemistry and Applied Biosciences, Institute of Pharmaceutical Sciences, Zürich, Switzerland.
Petrov D; ETH Zürich, Department of Chemistry and Applied Biosciences, Institute of Pharmaceutical Sciences, Zürich, Switzerland.
Scheuermann J; ETH Zürich, Department of Chemistry and Applied Biosciences, Institute of Pharmaceutical Sciences, Zürich, Switzerland. Electronic address: joerg.scheuermann@pharma.ethz.ch.

Trends Pharmacol Sci ; 44(11): 817-831, 2023 Nov.

Article em En | MEDLINE | ID: mdl-37739829

Palavras-chave

DNA-encoded chemical libraries; chelate effect; dual-display; encoded library technologies; fragment-based drug discovery; small-molecule drug discovery

Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2023 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2023 Tipo de documento: Article