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On-column capping of poly dT media-tethered mRNA accomplishes high capping efficiency, enhanced mRNA recovery, and improved stability against RNase.
Che, Shiyi; Feng, Xue; Li, Zhengjun; Su, Zhiguo; Ma, Guanghui; Li, Zhikao; Yu, Aibing; Liu, Minsu; Zhang, Songping.
Afiliação
  • Che S; State Key Laboratory of Biochemical Engineering, Institute of Process Engineering, Chinese Academy of Sciences, Beijing, China.
  • Feng X; Key Laboratory of Biopharmaceutical Preparation and Delivery, Chinese Academy of Sciences, Beijing, China.
  • Li Z; Department of Chemical and Biological Engineering, Monash University, Clayton, Victoria, Australia.
  • Su Z; Monash Suzhou Research Institute, Monash University, Suzhou, China.
  • Ma G; State Key Laboratory of Biochemical Engineering, Institute of Process Engineering, Chinese Academy of Sciences, Beijing, China.
  • Li Z; Key Laboratory of Biopharmaceutical Preparation and Delivery, Chinese Academy of Sciences, Beijing, China.
  • Yu A; Monash Suzhou Research Institute, Monash University, Suzhou, China.
  • Liu M; Department of Materials Science and Engineering, Monash University, Clayton, Victoria, Australia.
  • Zhang S; State Key Laboratory of Biochemical Engineering, Institute of Process Engineering, Chinese Academy of Sciences, Beijing, China.
Biotechnol Bioeng ; 121(1): 206-218, 2024 01.
Article em En | MEDLINE | ID: mdl-37747706

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Poli T / Ribonucleases Idioma: En Ano de publicação: 2024 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Poli T / Ribonucleases Idioma: En Ano de publicação: 2024 Tipo de documento: Article