MitoTam-01 Trial: Mitochondrial Targeting as Plausible Approach to Cancer Therapy. Comment on Yap et al. Complex I Inhibitor of Oxidative Phosphorylation in Advanced Solid Tumors and Acute Myeloid Leukemia: Phase I Trials. <i>Nat. Med.</i> 2023, <i>29</i>, 115-126.

Neuzil, Jiri; Rohlena, Jakub; Werner, Lukas; Bielcikova, Zuzana

MitoTam-01 Trial: Mitochondrial Targeting as Plausible Approach to Cancer Therapy. Comment on Yap et al. Complex I Inhibitor of Oxidative Phosphorylation in Advanced Solid Tumors and Acute Myeloid Leukemia: Phase I Trials. Nat. Med. 2023, 29, 115-126.

Neuzil, Jiri; Rohlena, Jakub; Werner, Lukas; Bielcikova, Zuzana.

Afiliação

Neuzil J; School of Pharmacy and Medical Science, Griffith University, Southport, Qld 4222, Australia.
Rohlena J; Institute of Biotechnology, Czech Academy of Sciences, 252 50 Prague, Czech Republic.
Werner L; Faculty of Science, Charles University, 128 00 Prague, Czech Republic.
Bielcikova Z; First Faculty of Medicine, Charles University, 121 08 Prague, Czech Republic.

Cancers (Basel) ; 15(18)2023 Sep 08.

Article em En | MEDLINE | ID: mdl-37760446

RESUMO

A recent paper published in Nature Medicine reported on the Phase I clinical trial of a mitochondria-targeting anti-cancer agent IACS-01059 in patients with acute myeloid leukemia (AML) and solid tumors [...].

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Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2023 Tipo de documento: Article