Effect of Combined Levothyroxine (L-T<sub>4</sub>) and 3-Iodothyronamine (T<sub>1</sub>AM) Supplementation on Memory and Adult Hippocampal Neurogenesis in a Mouse Model of Hypothyroidism.

Rutigliano, Grazia; Bertolini, Andrea; Grittani, Nicoletta; Frascarelli, Sabina; Carnicelli, Vittoria; Ippolito, Chiara; Moscato, Stefania; Mattii, Letizia; Kusmic, Claudia; Saba, Alessandro; Origlia, Nicola; Zucchi, Riccardo

Effect of Combined Levothyroxine (L-T₄) and 3-Iodothyronamine (T₁AM) Supplementation on Memory and Adult Hippocampal Neurogenesis in a Mouse Model of Hypothyroidism.

Rutigliano, Grazia; Bertolini, Andrea; Grittani, Nicoletta; Frascarelli, Sabina; Carnicelli, Vittoria; Ippolito, Chiara; Moscato, Stefania; Mattii, Letizia; Kusmic, Claudia; Saba, Alessandro; Origlia, Nicola; Zucchi, Riccardo.

Afiliação

Rutigliano G; Institute of Clinical Science, Imperial College London, London SW7 2AZ, UK.
Bertolini A; Department of Pathology, University of Pisa, 56126 Pisa, Italy.
Grittani N; CNR Institute of Clinical Physiology, 56124 Pisa, Italy.
Frascarelli S; Department of Pathology, University of Pisa, 56126 Pisa, Italy.
Carnicelli V; Department of Pathology, University of Pisa, 56126 Pisa, Italy.
Ippolito C; Department of Pathology, University of Pisa, 56126 Pisa, Italy.
Moscato S; Department of Pathology, University of Pisa, 56126 Pisa, Italy.
Mattii L; Department of Clinical and Experimental Medicine, University of Pisa, 56126 Pisa, Italy.
Kusmic C; Department of Clinical and Experimental Medicine, University of Pisa, 56126 Pisa, Italy.
Saba A; Department of Clinical and Experimental Medicine, University of Pisa, 56126 Pisa, Italy.
Origlia N; CNR Institute of Clinical Physiology, 56124 Pisa, Italy.
Zucchi R; Department of Pathology, University of Pisa, 56126 Pisa, Italy.

Int J Mol Sci ; 24(18)2023 Sep 08.

Article em En | MEDLINE | ID: mdl-37762153

Assuntos

Hipotireoidismo; Tiroxina; Camundongos; Animais; Tiroxina/metabolismo; Hipotireoidismo/tratamento farmacológico; Hipotireoidismo/metabolismo; Hipocampo/metabolismo; Suplementos Nutricionais; Proteínas do Tecido Nervoso/metabolismo; Fatores de Transcrição Hélice-Alça-Hélice Básicos/metabolismo

Palavras-chave

doublecortin; mass spectrometry; methimazole; neuroendocrinology; novel object recognition; thyroperoxidase

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Tiroxina / Hipotireoidismo Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Ano de publicação: 2023 Tipo de documento: Article

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