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Mechanistic modeling of semicontinuous fluidized bed drying of pharmaceutical granules by incorporating single particle and bulk drying kinetics.
Vandeputte, Tuur; Ghijs, Michael; Van Hauwermeiren, Daan; Dos Santos Schultz, Eduardo; Schäfer, Elisabeth; Stauffer, Fanny; De Beer, Thomas; Nopens, Ingmar.
Afiliação
  • Vandeputte T; BIOMATH, Department of Data Analysis and Mathematical Modelling, Ghent University, B-9000 Ghent, Belgium; Laboratory of Pharmaceutical Process Analytical Technology, Department of Pharmaceutical Analysis, Ghent University, B-9000 Ghent, Belgium.
  • Ghijs M; BIOMATH, Department of Data Analysis and Mathematical Modelling, Ghent University, B-9000 Ghent, Belgium; Laboratory of Pharmaceutical Process Analytical Technology, Department of Pharmaceutical Analysis, Ghent University, B-9000 Ghent, Belgium.
  • Van Hauwermeiren D; BIOMATH, Department of Data Analysis and Mathematical Modelling, Ghent University, B-9000 Ghent, Belgium; Laboratory of Pharmaceutical Process Analytical Technology, Department of Pharmaceutical Analysis, Ghent University, B-9000 Ghent, Belgium.
  • Dos Santos Schultz E; Discovery, Product Development & Supply, Janssen R&D, B-2340 Beerse, Belgium.
  • Schäfer E; Discovery, Product Development & Supply, Janssen R&D, B-2340 Beerse, Belgium.
  • Stauffer F; UCB Pharma S.A, B-1420 Braine-l'Alleud, Belgium.
  • De Beer T; Laboratory of Pharmaceutical Process Analytical Technology, Department of Pharmaceutical Analysis, Ghent University, B-9000 Ghent, Belgium. Electronic address: Thomas.DeBeer@Ugent.be.
  • Nopens I; BIOMATH, Department of Data Analysis and Mathematical Modelling, Ghent University, B-9000 Ghent, Belgium.
Int J Pharm ; 646: 123447, 2023 Nov 05.
Article em En | MEDLINE | ID: mdl-37770009

Texto completo: 1 Base de dados: MEDLINE Tipo de estudo: Prognostic_studies Idioma: En Ano de publicação: 2023 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Tipo de estudo: Prognostic_studies Idioma: En Ano de publicação: 2023 Tipo de documento: Article