The landscape of MHC-presented phosphopeptides yields actionable shared tumor antigens for cancer immunotherapy across multiple HLA alleles.

Molvi, Zaki; Klatt, Martin G; Dao, Tao; Urraca, Jessica; Scheinberg, David A; O'Reilly, Richard J

Molvi, Zaki; Klatt, Martin G; Dao, Tao; Urraca, Jessica; Scheinberg, David A; O'Reilly, Richard J.

Afiliação

Molvi Z; Immunology Program, Memorial Sloan Kettering Cancer Center, New York, New York, USA zakimolvi@gmail.com.
Klatt MG; Department of Hematology, Oncology and Tumor Immunology, Charite Universitatsmedizin Berlin, Berlin, Germany.
Dao T; German Cancer Research Center, Heidelberg, Baden-Württemberg, Germany.
Urraca J; Berlin Institute of Health at Charité -Universitätsmedizin Berlin, BIH Biomedical 13 Innovation Academy, BIH Charité Clinician Scientist Program, Berlin, Germany.
Scheinberg DA; Department of Pediatrics, Molecular Pharmacology Program, Memorial Sloan Kettering Cancer Center, New York, New York, USA.
O'Reilly RJ; Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, New York, USA.

J Immunother Cancer ; 11(9)2023 09.

Article em En | MEDLINE | ID: mdl-37775115

Assuntos

Neoplasias; Fosfopeptídeos; Humanos; Antígenos de Neoplasias; Alelos; Antígenos HLA-C; Antígenos de Histocompatibilidade; Neoplasias/genética; Neoplasias/terapia; Complexo Principal de Histocompatibilidade; Imunoterapia; Antígenos HLA-A

Palavras-chave

CD8-positive T-lymphocytes; antigen presentation; antigens; antigens, tumor-associated, carbohydrate; hematologic neoplasms

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Fosfopeptídeos / Neoplasias Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Ano de publicação: 2023 Tipo de documento: Article

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