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Trametinib activates endogenous neurogenesis and recovers neuropathology in a model of Alzheimer's disease.
Kim, Mi-Yeon; Kim, Mi Jeong; Lee, Changyeob; Lee, Juwon; Kim, Sang Seong; Hong, Sungho; Kim, Hyoung Tae; Seo, Jinsoo; Yoon, Ki-Jun; Han, Sungho.
Afiliação
  • Kim MY; Neuroscience Research Center, Genuv Inc., Seoul, 03175, Republic of Korea.
  • Kim MJ; Neuroscience Research Center, Genuv Inc., Seoul, 03175, Republic of Korea.
  • Lee C; Department of Brain Sciences, Daegu Gyeongbuk Institute of Science and Technology (DGIST), Daegu, 42988, Republic of Korea.
  • Lee J; Department of Brain Sciences, Daegu Gyeongbuk Institute of Science and Technology (DGIST), Daegu, 42988, Republic of Korea.
  • Kim SS; College of Pharmacy, Hanyang University ERICA, Gyeonggi-do, 15588, Republic of Korea.
  • Hong S; Department of Biomedical Science and Engineering, Gwangju Institute of Science and Technology, Gwangju, 61005, Republic of Korea.
  • Kim HT; Computational Neuroscience Unit, Okinawa Institute of Science and Technology, Okinawa, 904-0495, Japan.
  • Seo J; Neuroscience Research Center, Genuv Inc., Seoul, 03175, Republic of Korea.
  • Yoon KJ; Shaperon Inc., Seoul, 06373, Republic of Korea.
  • Han S; Department of Brain Sciences, Daegu Gyeongbuk Institute of Science and Technology (DGIST), Daegu, 42988, Republic of Korea.
Exp Mol Med ; 55(10): 2177-2189, 2023 10.
Article em En | MEDLINE | ID: mdl-37779138
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Doença de Alzheimer Limite: Animals / Humans Idioma: En Ano de publicação: 2023 Tipo de documento: Article
Texto completo
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XML
PubMed Links
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Doença de Alzheimer Limite: Animals / Humans Idioma: En Ano de publicação: 2023 Tipo de documento: Article