Optimization and validation of a bioanalytical HPLC-UV technique for simultaneous determination of underivatized phenylalanine and tyrosine in the blood for phenylketonuria diagnosis and monitoring.

Rabti, Hadjira; Amrane, Mounira; Lalaouna, Abdeldjalil; Flilissa, Abdenacer; Benguerba, Yacine

Rabti, Hadjira; Amrane, Mounira; Lalaouna, Abdeldjalil; Flilissa, Abdenacer; Benguerba, Yacine.

Afiliação

Rabti H; Laboratory of Cardiovascular Diseases with Genetic and Nutritional Origin (LMCGN), Ferhat Abbas-Setif 1 University, Setif, Algeria.
Amrane M; Department of Pharmaceutical Engineering, Faculty of Process Engineering, Salah Boubnider-Constantine 3 University, Constantine, Algeria.
Lalaouna A; Laboratory of Cardiovascular Diseases with Genetic and Nutritional Origin (LMCGN), Ferhat Abbas-Setif 1 University, Setif, Algeria.
Flilissa A; Mokhtari Abdelghani Cancer Center, Elbez, Setif, Algeria.
Benguerba Y; Analytical Chemistry Laboratory, Pharmacy Department, Faculty of Medicine, Salah Boubnider-Constantine 3 University, Constantine, Algeria.

Biomed Chromatogr ; 38(1): e5758, 2024 Jan.

Article em En | MEDLINE | ID: mdl-37795814

Assuntos

Fenilcetonúrias; Tirosina; Humanos; Fenilalanina; Cromatografia Líquida de Alta Pressão/métodos; Fenilcetonúrias/diagnóstico; Temperatura

Palavras-chave

HPLC-UV; biological samples; central composite experimental design; phenylalanine/tyrosine ratio; phenylketonuria

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Fenilcetonúrias / Tirosina Tipo de estudo: Diagnostic_studies Limite: Humans Idioma: En Ano de publicação: 2024 Tipo de documento: Article

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google