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A conserved isoleucine in the binding pocket of RIG-I controls immune tolerance to mitochondrial RNA.
de Regt, Ann Kristin; Anand, Kanchan; Ciupka, Katrin; Bender, Felix; Gatterdam, Karl; Putschli, Bastian; Fusshöller, David; Hilbig, Daniel; Kirchhoff, Alexander; Hunkler, Charlotte; Wolter, Steven; Grünewald, Agathe; Wallerath, Christina; Schuberth-Wagner, Christine; Ludwig, Janos; Paeschke, Katrin; Bartok, Eva; Hagelueken, Gregor; Hartmann, Gunther; Zillinger, Thomas; Geyer, Matthias; Schlee, Martin.
Afiliação
  • de Regt AK; Department of Clinical Chemistry and Clinical Pharmacology, University Hospital Bonn, Bonn, Germany.
  • Anand K; Institute of Structural Biology, University Hospital Bonn, Bonn, Germany.
  • Ciupka K; Department of Clinical Chemistry and Clinical Pharmacology, University Hospital Bonn, Bonn, Germany.
  • Bender F; Department of Clinical Chemistry and Clinical Pharmacology, University Hospital Bonn, Bonn, Germany.
  • Gatterdam K; Institute of Structural Biology, University Hospital Bonn, Bonn, Germany.
  • Putschli B; Department of Clinical Chemistry and Clinical Pharmacology, University Hospital Bonn, Bonn, Germany.
  • Fusshöller D; Institute of Structural Biology, University Hospital Bonn, Bonn, Germany.
  • Hilbig D; Department of Oncology, Hematology and Rheumatology, University Hospital Bonn, Bonn, Germany.
  • Kirchhoff A; Department of Clinical Chemistry and Clinical Pharmacology, University Hospital Bonn, Bonn, Germany.
  • Hunkler C; Department of Clinical Chemistry and Clinical Pharmacology, University Hospital Bonn, Bonn, Germany.
  • Wolter S; Department of Clinical Chemistry and Clinical Pharmacology, University Hospital Bonn, Bonn, Germany.
  • Grünewald A; Department of Clinical Chemistry and Clinical Pharmacology, University Hospital Bonn, Bonn, Germany.
  • Wallerath C; Department of Clinical Chemistry and Clinical Pharmacology, University Hospital Bonn, Bonn, Germany.
  • Schuberth-Wagner C; Department of Clinical Chemistry and Clinical Pharmacology, University Hospital Bonn, Bonn, Germany.
  • Ludwig J; Department of Clinical Chemistry and Clinical Pharmacology, University Hospital Bonn, Bonn, Germany.
  • Paeschke K; Department of Clinical Chemistry and Clinical Pharmacology, University Hospital Bonn, Bonn, Germany.
  • Bartok E; Department of Oncology, Hematology and Rheumatology, University Hospital Bonn, Bonn, Germany.
  • Hagelueken G; Department of Clinical Chemistry and Clinical Pharmacology, University Hospital Bonn, Bonn, Germany.
  • Hartmann G; Institute of Experimental Haematology and Transfusion Medicine, University Hospital Bonn, Bonn, Germany.
  • Zillinger T; Unit of Experimental Immunology, Department of Biomedical Sciences, Institute of Tropical Medicine, Antwerp, Belgium.
  • Geyer M; Institute of Structural Biology, University Hospital Bonn, Bonn, Germany.
  • Schlee M; Department of Clinical Chemistry and Clinical Pharmacology, University Hospital Bonn, Bonn, Germany.
Nucleic Acids Res ; 51(21): 11893-11910, 2023 Nov 27.
Article em En | MEDLINE | ID: mdl-37831086
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Receptores Imunológicos / Proteína DEAD-box 58 / Isoleucina Limite: Humans Idioma: En Ano de publicação: 2023 Tipo de documento: Article
Texto completo
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XML
PubMed Links
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Receptores Imunológicos / Proteína DEAD-box 58 / Isoleucina Limite: Humans Idioma: En Ano de publicação: 2023 Tipo de documento: Article