Effect of the Cannabinoid Agonist WIN 55,212-2 on Neuropathic and Visceral Pain Induced by a Non-Diarrheagenic Dose of the Antitumoral Drug 5-Fluorouracil in the Rat.

Vera, Gema; López-Gómez, Laura; Girón, Rocío; Martín-Fontelles, María Isabel; Nurgali, Kulmira; Abalo, Raquel; Uranga, José Antonio

Vera, Gema; López-Gómez, Laura; Girón, Rocío; Martín-Fontelles, María Isabel; Nurgali, Kulmira; Abalo, Raquel; Uranga, José Antonio.

Afiliação

Vera G; Department of Basic Health Sciences, Faculty of Health Sciences, University Rey Juan Carlos (URJC), 28922 Alcorcón, Spain.
López-Gómez L; High Performance Research Group in Physiopathology and Pharmacology of the Digestive System (NeuGut-URJC), University Rey Juan Carlos (URJC), 28922 Alcorcón, Spain.
Girón R; Associated I+D+i Unit to the Institute of Medicinal Chemistry (IQM), Scientific Research Superior Council (CSIC), 28006 Madrid, Spain.
Martín-Fontelles MI; Department of Basic Health Sciences, Faculty of Health Sciences, University Rey Juan Carlos (URJC), 28922 Alcorcón, Spain.
Nurgali K; High Performance Research Group in Physiopathology and Pharmacology of the Digestive System (NeuGut-URJC), University Rey Juan Carlos (URJC), 28922 Alcorcón, Spain.
Abalo R; Department of Basic Health Sciences, Faculty of Health Sciences, University Rey Juan Carlos (URJC), 28922 Alcorcón, Spain.
Uranga JA; Associated I+D+i Unit to the Institute of Medicinal Chemistry (IQM), Scientific Research Superior Council (CSIC), 28006 Madrid, Spain.

Int J Mol Sci ; 24(19)2023 Sep 22.

Article em En | MEDLINE | ID: mdl-37833878

Assuntos

Canabinoides; Mucosite; Neuralgia; Dor Visceral; Humanos; Ratos; Masculino; Animais; Ratos Wistar; Agonistas de Receptores de Canabinoides/uso terapêutico; Dor Visceral/tratamento farmacológico; Dor Visceral/etiologia; Mucosite/tratamento farmacológico; Fluoruracila/efeitos adversos; Benzoxazinas/farmacologia; Benzoxazinas/uso terapêutico; Neuralgia/tratamento farmacológico; Neuralgia/induzido quimicamente; Canabinoides/farmacologia; Hiperalgesia/tratamento farmacológico; Hiperalgesia/induzido quimicamente; Diarreia/tratamento farmacológico

Palavras-chave

cancer chemotherapy; cannabinoid; chemotherapy-induced adverse effects; gastrointestinal motor function; peripheral neuropathy; visceral pain

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Canabinoides / Mucosite / Dor Visceral / Neuralgia Limite: Animals / Humans / Male Idioma: En Ano de publicação: 2023 Tipo de documento: Article

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