MicroRNA as Possible Mediators of the Synergistic Effect of Celecoxib and Glucosamine Sulfate in Human Osteoarthritic Chondrocyte Exposed to IL-1ß.

Cheleschi, Sara; Veronese, Nicola; Carta, Serafino; Collodel, Giulia; Bottaro, Maria; Moretti, Elena; Corsaro, Roberta; Barbarino, Marcella; Fioravanti, Antonella

Cheleschi, Sara; Veronese, Nicola; Carta, Serafino; Collodel, Giulia; Bottaro, Maria; Moretti, Elena; Corsaro, Roberta; Barbarino, Marcella; Fioravanti, Antonella.

Afiliação

Cheleschi S; Rheumatology Unit, Department of Medicine, Surgery and Neuroscience, Azienda Ospedaliera Universitaria Senese, Policlinico Le Scotte, 53100 Siena, Italy.
Veronese N; Geriatric Unit, Department of Internal Medicine and Geriatrics, University of Palermo, Viale Scaduto, 90100 Palermo, Italy.
Carta S; Section of Orthopedics and Traumatology, Department of Medicine, Surgery and Neurosciences, University of Siena, Policlinico Le Scotte, 53100 Siena, Italy.
Collodel G; Department of Molecular and Developmental Medicine, University of Siena, 53100 Siena, Italy.
Bottaro M; Department of Medical Biotechnologies, University of Siena, 53100 Siena, Italy.
Moretti E; Center for Biotechnology, Sbarro Institute for Cancer Research and Molecular Medicine, College of Science and Technology, Temple University, Philadelphia, PA 19122, USA.
Corsaro R; Department of Molecular and Developmental Medicine, University of Siena, 53100 Siena, Italy.
Barbarino M; Department of Molecular and Developmental Medicine, University of Siena, 53100 Siena, Italy.
Fioravanti A; Department of Medical Biotechnologies, University of Siena, 53100 Siena, Italy.

Int J Mol Sci ; 24(19)2023 Oct 08.

Article em En | MEDLINE | ID: mdl-37834442

Assuntos

MicroRNAs; Humanos; MicroRNAs/metabolismo; Glucosamina/farmacologia; Glucosamina/metabolismo; Celecoxib/farmacologia; Celecoxib/metabolismo; Espécies Reativas de Oxigênio/metabolismo; Condrócitos/metabolismo; Células Cultivadas; Interleucina-1beta/metabolismo; NF-kappa B/metabolismo; Apoptose

Palavras-chave

NF-κB; celecoxib; chondrocytes; chondroprotection; glucosamine sulfate; inflammation; microRNA; osteoarthritis

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: MicroRNAs Limite: Humans Idioma: En Ano de publicação: 2023 Tipo de documento: Article

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: MicroRNAs Limite: Humans Idioma: En Ano de publicação: 2023 Tipo de documento: Article