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SRCAP mutations drive clonal hematopoiesis through epigenetic and DNA repair dysregulation.
Chen, Chun-Wei; Zhang, Linda; Dutta, Ravi; Niroula, Abhishek; Miller, Peter G; Gibson, Christopher J; Bick, Alexander G; Reyes, Jaime M; Lee, Yi-Tang; Tovy, Ayala; Gu, Tianpeng; Waldvogel, Sarah; Chen, Yi-Hung; Venters, Bryan J; Estève, Pierre-Olivier; Pradhan, Sriharsa; Keogh, Michael-Christopher; Natarajan, Pradeep; Takahashi, Koichi; Sperling, Adam S; Goodell, Margaret A.
Afiliação
  • Chen CW; Interdepartmental Program in Integrative Molecular and Biomedical Sciences, Baylor College of Medicine, Houston, TX, USA; Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX, USA; Stem Cells and Regenerative Medicine Center, Baylor College of Medicine, Houston, TX,
  • Zhang L; Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX, USA; Stem Cells and Regenerative Medicine Center, Baylor College of Medicine, Houston, TX, USA; Program in Translational Biology and Molecular Medicine, Houston, TX, USA; Medical Scientist Training Program, Baylor
  • Dutta R; Division of Hematology, Brigham and Women's Hospital, Boston, MA, USA.
  • Niroula A; Broad Institute of MIT and Harvard, Cambridge, MA, USA; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.
  • Miller PG; Division of Hematology, Brigham and Women's Hospital, Boston, MA, USA; Center for Cancer Research and Center for Regenerative Medicine, Massachusetts General Hospital, Boston, MA, USA.
  • Gibson CJ; Broad Institute of MIT and Harvard, Cambridge, MA, USA.
  • Bick AG; Division of Hematology, Brigham and Women's Hospital, Boston, MA, USA; Division of Genetic Medicine, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.
  • Reyes JM; Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX, USA; Stem Cells and Regenerative Medicine Center, Baylor College of Medicine, Houston, TX, USA.
  • Lee YT; Interdepartmental Program in Integrative Molecular and Biomedical Sciences, Baylor College of Medicine, Houston, TX, USA; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX, USA.
  • Tovy A; Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX, USA; Stem Cells and Regenerative Medicine Center, Baylor College of Medicine, Houston, TX, USA.
  • Gu T; Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX, USA; Stem Cells and Regenerative Medicine Center, Baylor College of Medicine, Houston, TX, USA.
  • Waldvogel S; Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX, USA; Stem Cells and Regenerative Medicine Center, Baylor College of Medicine, Houston, TX, USA; Medical Scientist Training Program, Baylor College of Medicine, Houston, TX, USA.
  • Chen YH; Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX, USA.
  • Venters BJ; EpiCypher Inc., Durham, NC, USA.
  • Estève PO; New England Biolabs, Ipswich, MA, USA.
  • Pradhan S; New England Biolabs, Ipswich, MA, USA.
  • Keogh MC; EpiCypher Inc., Durham, NC, USA.
  • Natarajan P; Division of Hematology, Brigham and Women's Hospital, Boston, MA, USA; Cardiovascular Research Center, Massachusetts General Hospital, Boston, MA, USA; Department of Medicine, Harvard Medical School, Boston, MA, USA.
  • Takahashi K; Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
  • Sperling AS; Division of Hematology, Brigham and Women's Hospital, Boston, MA, USA; Broad Institute of MIT and Harvard, Cambridge, MA, USA; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.
  • Goodell MA; Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX, USA; Stem Cells and Regenerative Medicine Center, Baylor College of Medicine, Houston, TX, USA; Medical Scientist Training Program, Baylor College of Medicine, Houston, TX, USA. Electronic address: goodell@bcm.edu
Cell Stem Cell ; 30(11): 1503-1519.e8, 2023 11 02.
Article em En | MEDLINE | ID: mdl-37863054

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Hematopoiese Clonal / Hematopoese Limite: Animals / Humans Idioma: En Ano de publicação: 2023 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Hematopoiese Clonal / Hematopoese Limite: Animals / Humans Idioma: En Ano de publicação: 2023 Tipo de documento: Article