Regulation of anti-inflammatory and antioxidant responses by methanol extract of Mikania cordata (Burm. f.) B. L. Rob. leaves via the inactivation of NF-&#954;B and MAPK signaling pathways and activation of Nrf2 in LPS-induced RAW 264.7 macrophages.

Kang, Eunjeong; Lee, Junho; Seo, Sumin; Uddin, Salah; Lee, Sangwoo; Han, Sang Beom; Cho, Sayeon

Regulation of anti-inflammatory and antioxidant responses by methanol extract of Mikania cordata (Burm. f.) B. L. Rob. leaves via the inactivation of NF-κB and MAPK signaling pathways and activation of Nrf2 in LPS-induced RAW 264.7 macrophages.

Kang, Eunjeong; Lee, Junho; Seo, Sumin; Uddin, Salah; Lee, Sangwoo; Han, Sang Beom; Cho, Sayeon.

Afiliação

Kang E; Laboratory of Molecular and Pharmacological Cell Biology, College of Pharmacy, Chung-Ang University, Seoul 06974, Republic of Korea.
Lee J; Laboratory of Molecular and Pharmacological Cell Biology, College of Pharmacy, Chung-Ang University, Seoul 06974, Republic of Korea.
Seo S; Laboratory of Biomedical Mass Spectrometry, College of Pharmacy, Chung-Ang University, Seoul 06974, Republic of Korea.
Uddin S; Ethnobotanical Database of Bangladesh, Tejgaon Dhaka, 1208, Bangladesh.
Lee S; International Biological Material Research Center, Korea Research Institute of Bioscience and Biotechnology, Daejeon 34141, Republic of Korea.
Han SB; Laboratory of Biomedical Mass Spectrometry, College of Pharmacy, Chung-Ang University, Seoul 06974, Republic of Korea.
Cho S; Laboratory of Molecular and Pharmacological Cell Biology, College of Pharmacy, Chung-Ang University, Seoul 06974, Republic of Korea. Electronic address: sycho@cau.ac.kr.

Biomed Pharmacother ; 168: 115746, 2023 Dec.

Article em En | MEDLINE | ID: mdl-37864893

Assuntos

Mikania; NF-kappa B; Animais; Camundongos; Anti-Inflamatórios/farmacologia; Anti-Inflamatórios/uso terapêutico; Antioxidantes/metabolismo; Citocinas/metabolismo; Inflamação/induzido quimicamente; Inflamação/tratamento farmacológico; Inflamação/metabolismo; Proteína 1 Associada a ECH Semelhante a Kelch/metabolismo; Lipopolissacarídeos/imunologia; Macrófagos/metabolismo; Sistema de Sinalização das MAP Quinases; Metanol; Mikania/metabolismo; Fator 2 Relacionado a NF-E2/metabolismo; NF-kappa B/metabolismo; Óxido Nítrico Sintase Tipo II/metabolismo; Células RAW 264.7; RNA Mensageiro/metabolismo

Palavras-chave

Mikania cordata (Burm. f.) B.L.Rob; Mitogenactivated protein kinases; Nuclear factor erythroid-2-related factor 2; Nuclear factor kappa B; RAW 264.7 macrophages

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: NF-kappa B / Mikania Limite: Animals Idioma: En Ano de publicação: 2023 Tipo de documento: Article

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: NF-kappa B / Mikania Limite: Animals Idioma: En Ano de publicação: 2023 Tipo de documento: Article