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Lipid Nanoparticle Encapsulation Empowers Poly(I:C) to Activate Cytoplasmic RLRs and Thereby Increases Its Adjuvanticity.
Lamoot, Alexander; Jangra, Sonia; Laghlali, Gabriel; Warang, Prajakta; Singh, Gagandeep; Chang, Lauren A; Park, Seok-Chan; Singh, Gagandeep; De Swarte, Kim; Zhong, Zifu; Louage, Benoit; De Lombaerde, Emily; Ye, Tingting; Chen, Yong; Cuadrado-Castano, Sara; Lienenklaus, Stefan; Sanders, Niek N; Lambrecht, Bart N; García-Sastre, Adolfo; Schotsaert, Michael; De Geest, Bruno G.
Afiliação
  • Lamoot A; Department of Pharmaceutics, Ghent University, Ghent, 9000, Belgium.
  • Jangra S; Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.
  • Laghlali G; Global Health and Emerging Pathogens Institute, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.
  • Warang P; Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.
  • Singh G; Global Health and Emerging Pathogens Institute, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.
  • Chang LA; Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.
  • Park SC; Global Health and Emerging Pathogens Institute, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.
  • Singh G; Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.
  • De Swarte K; Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.
  • Zhong Z; Global Health and Emerging Pathogens Institute, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.
  • Louage B; Graduate School of Biomedical Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.
  • De Lombaerde E; Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.
  • Ye T; Global Health and Emerging Pathogens Institute, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.
  • Chen Y; Biosafety Research Institute, College of Veterinary Medicine, Jeonbuk National University, Iksan, 54596, South Korea.
  • Cuadrado-Castano S; Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.
  • Lienenklaus S; Global Health and Emerging Pathogens Institute, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.
  • Sanders NN; Laboratory of Mucosal Immunology, VIB-UGent Center for Inflammation Research, Ghent University, Ghent, 9000, Belgium.
  • Lambrecht BN; Department of Internal Medicine and Pediatrics, Faculty of Medicine and Health Sciences, Ghent University, Ghent, 9000, Belgium.
  • García-Sastre A; Department of Respiratory Medicine, Ghent University Hospital, Ghent, 9000, Belgium.
  • Schotsaert M; Department of Pharmaceutics, Ghent University, Ghent, 9000, Belgium.
  • De Geest BG; Department of Pharmaceutics, Ghent University, Ghent, 9000, Belgium.
Small ; 20(10): e2306892, 2024 Mar.
Article em En | MEDLINE | ID: mdl-37867244
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Poli I-C / Receptor 3 Toll-Like / Nanopartículas / Glicoproteína da Espícula de Coronavírus / Lipossomos Limite: Animals / Humans Idioma: En Ano de publicação: 2024 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Poli I-C / Receptor 3 Toll-Like / Nanopartículas / Glicoproteína da Espícula de Coronavírus / Lipossomos Limite: Animals / Humans Idioma: En Ano de publicação: 2024 Tipo de documento: Article