Protocol and statistical analysis plan for the mega randomised registry trial comparing conservative vs. liberal oxygenation targets in adults with sepsis in the intensive care unit (Mega-ROX Sepsis).

Young, Paul J; Al-Fares, Abdulrahman; Aryal, Diptesh; Arabi, Yaseen M; Ashraf, Muhammad Sheharyar; Bagshaw, Sean M; Beane, Abigail; de Oliveira Manoel, Airton L; Dullawe, Layoni; Fazla, Fathima; Fujii, Tomoko; Haniffa, Rashan; Hodgson, Carol L; Hunt, Anna; Tirupakuzhi Vijayaraghavan, Bharath Kumar; Landoni, Giovanni; Lawrence, Cassie; Maia, Israel Silva; Mackle, Diane; Mazlan, Mohd Zulfakar; Nichol, Alistair D; Olatunji, Shaanti; Rashan, Aasiyah; Rashan, Sumayyah; Kasza, Jessica

Young, Paul J; Al-Fares, Abdulrahman; Aryal, Diptesh; Arabi, Yaseen M; Ashraf, Muhammad Sheharyar; Bagshaw, Sean M; Beane, Abigail; de Oliveira Manoel, Airton L; Dullawe, Layoni; Fazla, Fathima; Fujii, Tomoko; Haniffa, Rashan; Hodgson, Carol L; Hunt, Anna; Tirupakuzhi Vijayaraghavan, Bharath Kumar; Landoni, Giovanni; Lawrence, Cassie; Maia, Israel Silva; Mackle, Diane; Mazlan, Mohd Zulfakar; Nichol, Alistair D; Olatunji, Shaanti; Rashan, Aasiyah; Rashan, Sumayyah; Kasza, Jessica.

Afiliação

Young PJ; Intensive Care Unit, Wellington Hospital, Wellington, New Zealand.
Al-Fares A; Medical Research Institute of New Zealand, Wellington, New Zealand.
Aryal D; Australian and New Zealand Intensive Care Research Centre, Monash University, Melbourne, Victoria, Australia.
Arabi YM; Department of Critical Care, University of Melbourne, Melbourne, Victoria, Australia.
Ashraf MS; Department of Anesthesia, Critical Care Medicine, and Pain Medicine, Al-Amiri Hospital, Ministry of Health, Kuwait.
Bagshaw SM; Kuwait Extracorporeal Life Support Program, Al-Amiri Center for Respiratory and Cardiac Failure, Ministry of Health, Kuwait.
Beane A; Nepal Intensive Care Research Foundation, Kathmandu, Nepal.
de Oliveira Manoel AL; College of Medicine, King Saud Bin Abdulaziz University for Health Sciences, King Abdullah International Medical Research Center, and Intensive Care Department, King Abdulaziz Medical City, Ministry of National Guard Health Affairs, Riyadh, Saudi Arabia.
Dullawe L; Department of Anesthesia and Critical Care Unit, Lady Reading Hospital, Peshawar, Pakistan.
Fazla F; Department of Critical Care Medicine, University of Alberta, and Alberta Health Services, Edmonton, Alberta, Canada.
Fujii T; Centre for Inflammation Research, University of Edinburgh, Edinburgh, United Kingdom.
Haniffa R; National Intensive Care Surveillance - MORU (NICS-MORU), Colombo, Sri Lanka.
Hodgson CL; Department of Critical Care Medicine, Sultan Qaboos Comprehensive Cancer Care and Research Center, Muscat, Oman.
Hunt A; National Intensive Care Surveillance - MORU (NICS-MORU), Colombo, Sri Lanka.
Tirupakuzhi Vijayaraghavan BK; National Intensive Care Surveillance - MORU (NICS-MORU), Colombo, Sri Lanka.
Landoni G; Australian and New Zealand Intensive Care Research Centre, Monash University, Melbourne, Victoria, Australia.
Lawrence C; Intensive Care Unit, Jikei University Hospital, Tokyo, Japan.
Maia IS; Department of Health Promotion and Human Behavior, Kyoto University School of Public Health, Kyoto, Japan.
Mackle D; Centre for Inflammation Research, University of Edinburgh, Edinburgh, United Kingdom.
Mazlan MZ; National Intensive Care Surveillance - MORU (NICS-MORU), Colombo, Sri Lanka.
Nichol AD; Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom.
Olatunji S; University College Hospital, London, United Kingdom.
Rashan A; Australian and New Zealand Intensive Care Research Centre, Monash University, Melbourne, Victoria, Australia.
Rashan S; Department of Critical Care, University of Melbourne, Melbourne, Victoria, Australia.
Kasza J; The Intensive Care Unit, Alfred Health, Melbourne, Victoria, Australia.