TMEM241 is a UDP-N-acetylglucosamine transporter required for M6P modification of NPC2 and cholesterol transport.

Zhao, Nan; Deng, Gang; Yuan, Pei-Xin; Zhang, Ya-Fen; Jiang, Lu-Yi; Zhao, Xiaolu; Song, Bao-Liang

Zhao, Nan; Deng, Gang; Yuan, Pei-Xin; Zhang, Ya-Fen; Jiang, Lu-Yi; Zhao, Xiaolu; Song, Bao-Liang.

Afiliação

Zhao N; The Institute for Advanced Studies, Hubei Key Laboratory of Cell Homeostasis, College of Life Sciences, Taikang Center for Life and Medical Sciences, Taikang Medical School, Wuhan University, Wuhan, China.
Deng G; The Institute for Advanced Studies, Hubei Key Laboratory of Cell Homeostasis, College of Life Sciences, Taikang Center for Life and Medical Sciences, Taikang Medical School, Wuhan University, Wuhan, China.
Yuan PX; The Institute for Advanced Studies, Hubei Key Laboratory of Cell Homeostasis, College of Life Sciences, Taikang Center for Life and Medical Sciences, Taikang Medical School, Wuhan University, Wuhan, China.
Zhang YF; The Institute for Advanced Studies, Hubei Key Laboratory of Cell Homeostasis, College of Life Sciences, Taikang Center for Life and Medical Sciences, Taikang Medical School, Wuhan University, Wuhan, China.
Jiang LY; The Institute for Advanced Studies, Hubei Key Laboratory of Cell Homeostasis, College of Life Sciences, Taikang Center for Life and Medical Sciences, Taikang Medical School, Wuhan University, Wuhan, China.
Zhao X; The Institute for Advanced Studies, Hubei Key Laboratory of Cell Homeostasis, College of Life Sciences, Taikang Center for Life and Medical Sciences, Taikang Medical School, Wuhan University, Wuhan, China. Electronic address: zhaoxiaolu@whu.edu.cn.
Song BL; The Institute for Advanced Studies, Hubei Key Laboratory of Cell Homeostasis, College of Life Sciences, Taikang Center for Life and Medical Sciences, Taikang Medical School, Wuhan University, Wuhan, China. Electronic address: blsong@whu.edu.cn.

J Lipid Res ; 64(12): 100465, 2023 12.

Article em En | MEDLINE | ID: mdl-37890669

Assuntos

Colesterol; Proteínas de Transporte Vesicular; Animais; Camundongos; Proteínas de Transporte Vesicular/metabolismo; Colesterol/metabolismo; Difosfato de Uridina/metabolismo; Lisossomos/metabolismo

Palavras-chave

Golgi apparatus; LDL; cholesterol trafficking; genome-wide CRISPR screen; lipid transfer proteins; lipids; lysosomal protein sorting; nucleotide sugar transporter

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Colesterol / Proteínas de Transporte Vesicular Limite: Animals Idioma: En Ano de publicação: 2023 Tipo de documento: Article

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