Perioperative proximal splenic artery embolization in cirrhotic patients with splenomegaly.
Minim Invasive Ther Allied Technol
; 33(1): 35-42, 2024 Feb.
Article
em En
| MEDLINE
| ID: mdl-37909461
ABSTRACT
INTRODUCTION:
The purpose of this study was to determine the effect of proximal splenic artery embolization (SAE) in cirrhotic patients with splenomegaly who underwent surgical laparotomy. MATERIAL ANDMETHODS:
This retrospective observational study included 8 cirrhotic patients with splenomegaly. They underwent proximal SAE before- (n = 6) or after (n = 2) laparotomy. Vascular plugs or coils were placed in the proximal splenic artery. The diameter of the portal vein and the splenic volume were recorded. Clinical outcome assessments included platelet counts, the model for end-stage liver disease (MELD) score, and complications.RESULTS:
After embolization, the portal venous diameter was significantly smaller (pre 13.6 ± 2.7 mm, post 12.5 ± 2.3 mm, p = 0.023), the splenic volume was significantly decreased (pre 463.2 ± 145.7 ml, post 373.3 ± 108.5 ml, p = 0.008) and the platelet count was significantly higher (pre 69.6 ± 30.8 × 103/µl, post 86.8 ± 27.7 × 103/µl, p = 0.035). Before embolization, the median MELD score was 12; after embolization, it was 11 (p = 0.026). No patient developed post-treatment complications after embolization.CONCLUSIONS:
The reduction of hypersplenism by perioperative proximal SAE may be safe and reduce the surgical risk in cirrhotic patients with splenomegaly.Palavras-chave
Texto completo:
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Base de dados:
MEDLINE
Assunto principal:
Embolização Terapêutica
/
Doença Hepática Terminal
/
Hipertensão Portal
Limite:
Humans
Idioma:
En
Ano de publicação:
2024
Tipo de documento:
Article