MARCH5 promotes STING pathway activation by suppressing polymer formation of oxidized STING.

Son, Kyungpyo; Jeong, Seokhwan; Eom, Eunchong; Kwon, Dohyeong; Kang, Suk-Jo

Son, Kyungpyo; Jeong, Seokhwan; Eom, Eunchong; Kwon, Dohyeong; Kang, Suk-Jo.

Afiliação

Son K; Department of Biological Sciences, Korea Advanced Institute of Science and Technology, Daejeon, Republic of Korea.
Jeong S; Department of Biological Sciences, Korea Advanced Institute of Science and Technology, Daejeon, Republic of Korea.
Eom E; Department of Biological Sciences, Korea Advanced Institute of Science and Technology, Daejeon, Republic of Korea.
Kwon D; Department of Biological Sciences, Korea Advanced Institute of Science and Technology, Daejeon, Republic of Korea.
Kang SJ; Department of Biological Sciences, Korea Advanced Institute of Science and Technology, Daejeon, Republic of Korea.

EMBO Rep ; 24(12): e57496, 2023 Dec 06.

Article em En | MEDLINE | ID: mdl-37916870

Assuntos

Mitocôndrias; Ubiquitina-Proteína Ligases; Animais; Camundongos; Imunidade Inata; Mitocôndrias/metabolismo; Polímeros/metabolismo; Transdução de Sinais; Ubiquitina-Proteína Ligases/genética; Ubiquitina-Proteína Ligases/metabolismo; Ubiquitinação

Palavras-chave

MARCH5; STING; oxidation; polymer; ubiquitination

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Ubiquitina-Proteína Ligases / Mitocôndrias Limite: Animals Idioma: En Ano de publicação: 2023 Tipo de documento: Article

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