Your browser doesn't support javascript.
loading
Coronary computed tomography angiography-based SYNTAX score for comprehensive assessment of advanced coronary artery disease.
Kageyama, Shigetaka; Serruys, Patrick W; Kotoku, Nozomi; Garg, Scot; Ninomiya, Kai; Masuda, Shinichiro; Morel, Marie-Angele; Taylor, Charles A; Rogers, Campbell; Thomsen, Brian; Pontone, Gianluca; Pompilio, Giulio; Puskas, John D; Doenst, Torsten; La Meir, Mark; Teichgräber, Ulf; Gupta, Himanshu; De Mey, Johan; Andreini, Daniele; Onuma, Yoshinobu.
Afiliação
  • Kageyama S; Department of Cardiology, University of Galway, Galway, Ireland; CORRIB Research Centre for Advanced Imaging and Core Lab, University of Galway, Galway, Ireland.
  • Serruys PW; Department of Cardiology, University of Galway, Galway, Ireland; CORRIB Research Centre for Advanced Imaging and Core Lab, University of Galway, Galway, Ireland. Electronic address: patrick.w.j.c.serruys@gmail.com.
  • Kotoku N; Department of Cardiology, University of Galway, Galway, Ireland; CORRIB Research Centre for Advanced Imaging and Core Lab, University of Galway, Galway, Ireland.
  • Garg S; Department of Cardiology, Royal Blackburn Hospital, Blackburn, UK.
  • Ninomiya K; Department of Cardiology, University of Galway, Galway, Ireland; CORRIB Research Centre for Advanced Imaging and Core Lab, University of Galway, Galway, Ireland.
  • Masuda S; Department of Cardiology, University of Galway, Galway, Ireland; CORRIB Research Centre for Advanced Imaging and Core Lab, University of Galway, Galway, Ireland.
  • Morel MA; CORRIB Research Centre for Advanced Imaging and Core Lab, University of Galway, Galway, Ireland.
  • Taylor CA; HeartFlow, Mountain View, CA, USA.
  • Rogers C; HeartFlow, Mountain View, CA, USA.
  • Thomsen B; Global Research Team, GE Healthcare US, Milwaukee, WI, USA.
  • Pontone G; Department of Cardiovascular Imaging, Centro Cardiologico Monzino IRCCS, Milan, Italy.
  • Pompilio G; Unit of Vascular Biology and Regenerative Medicine, Centro Cardiologico Monzino IRCCS, Milano, Italy; Dipartimento di Scienze Cliniche, Chirurgiche ed Odontoiatriche, Università degli Studi di Milano, Milano, Italy.
  • Puskas JD; Department of Cardiovascular Surgery, Mount Sinai Morningside, New York, NY, USA.
  • Doenst T; Department of Cardiothoracic Surgery, University Hospital Jena, Jena, Germany.
  • La Meir M; Cardiac Surgery Department, Universitair Ziekenhuis Brussels, VUB, Brussels, Belgium.
  • Teichgräber U; Department of Radiology, University Hospital Jena, Jena, Germany.
  • Gupta H; Cardiac Imaging, Valley Health System, Ridgewood, NJ, USA.
  • De Mey J; Department of Radiology, Universitair Ziekenhuis Brussels, Brussels, Belgium.
  • Andreini D; Division of Cardiology and Cardiac Imaging, IRCCS Galeazzi Sant'Ambrogio, Milan, Italy; Department of Biomedical and Clinical Sciences, University of Milan, Milan, Italy.
  • Onuma Y; Department of Cardiology, University of Galway, Galway, Ireland.
J Cardiovasc Comput Tomogr ; 18(2): 120-136, 2024.
Article em En | MEDLINE | ID: mdl-37923578
ABSTRACT

BACKGROUND:

Since the initial attempt to adapt the anatomical SYNTAX score (aSS) to coronary computed tomography angiography (CCTA), CCTA imaging technology has evolved, and is currently used as a "decision-maker" for revascularization strategy in complex coronary artery disease (CAD) and has rendered necessary some updating of the aSS to the CCTA modality.

OBJECTIVES:

The aim is to provide updated definitions of the aSS derived from CCTA in patients with complex CAD undergoing CABG.

METHODS:

The modifications of CCTA-aSS are the following; (i) updated definition and detection criteria of total occlusion (TO) in CCTA based on length assessment, (ii) inclusion of scoring points for serial bifurcations located in one single coronary segment. (iii) inclusion of weighing score points for lesions located distal to a TO, not visualized on conventional coronary angiography, but visible in CCTA, (iv) removal of thrombus and bridging collateral items from the weighing score, considering the limited diagnostic capability of CCTA in detecting these specific lesion characteristics.

RESULTS:

the updated CCTA-aSS was tested in a first-in-man study using the sole guidance of CCTA for the planning and performance of bypass surgery in complex CAD (n â€‹= â€‹114). An interobserver analysis showed excellent reproducibility (ICC â€‹= â€‹0.96, 95 â€‹% confidence interval 0.94-0.97).

CONCLUSION:

The updated CCTA-aSS was implemented in a cohort of patients with complex CAD undergoing CABG with the sole guidance of CCTA and FFRCT and the Inter-reproducibility of the analysis of the updated score was found excellent. The prognostic value of the modified CCTA-aSS will be examined in future studies.
Assuntos
Palavras-chave
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Doença da Artéria Coronariana / Estenose Coronária Limite: Humans Idioma: En Ano de publicação: 2024 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Doença da Artéria Coronariana / Estenose Coronária Limite: Humans Idioma: En Ano de publicação: 2024 Tipo de documento: Article