Associations between the aetiology of preterm birth and mortality and neurodevelopment up to 11 years.
Acta Paediatr
; 113(3): 471-479, 2024 Mar.
Article
em En
| MEDLINE
| ID: mdl-37926858
ABSTRACT
AIM:
To investigate how the aetiology of very preterm birth/very low birth weight is associated with mortality and later neurodevelopmental outcomes.METHODS:
Very preterm/very low-birth weight singletons were categorised based on the aetiology of preterm birth spontaneous preterm birth (n = 47, 28.1%), preterm premature rupture of membranes (n = 56, 33.5%) or placental vascular pathology (n = 64, 38.3%). Mortality, cerebral palsy, severe cognitive impairment by 11 years of age (<2SD) and mean full-scale intelligence quotient at 11 years were studied in association with birth aetiology.RESULTS:
There was no difference in mortality or rate of cerebral palsy according to birth aetiologies. The rate of severe cognitive impairment was lower (4.9% vs. 15.3%) in the preterm premature rupture of the membrane group in comparison to the placental vascular pathology group (OR 0.2, 95% CI 0.03-0.9, adjusted for gestational age). At 11 years, there was no statistically significant difference in the mean full-scale intelligence quotient.CONCLUSION:
Placental vascular pathology, as the aetiology of very preterm birth/very low birth weight, is associated with a higher rate of severe cognitive impairments in comparison to preterm premature rupture of membranes, although there was no difference in the mean full-scale intelligence quotient at 11 years. The aetiology of very preterm birth/very low birth weight was not associated with mortality or the rate of cerebral palsy.Palavras-chave
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Ruptura Prematura de Membranas Fetais
/
Paralisia Cerebral
/
Nascimento Prematuro
Limite:
Child
/
Female
/
Humans
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Newborn
/
Pregnancy
Idioma:
En
Ano de publicação:
2024
Tipo de documento:
Article