Establishing Control Frequency of Embryonic and Fetal Loss in a Mutant Mouse Colony.
Cold Spring Harb Protoc
; 2024(1): pdb.prot108083, 2024 Jan 02.
Article
em En
| MEDLINE
| ID: mdl-37932079
ABSTRACT
In the analysis of prenatal lethal recessive mutations, one must account for embryonic losses that are not related to the mutant phenotype. This protocol details the way to determine what the background level of unrelated embryonic loss is by a simple backcrossing strategy in the particular mouse strain that carries the lethal recessive mutation.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Mutação
Limite:
Animals
/
Pregnancy
Idioma:
En
Ano de publicação:
2024
Tipo de documento:
Article