Discovery of plant-derived anti-tumor natural products: Potential leads for anti-tumor drug discovery.
Bioorg Chem
; 142: 106957, 2024 01.
Article
em En
| MEDLINE
| ID: mdl-37939507
ABSTRACT
Natural products represent a paramount source of novel drugs. Numerous plant-derived natural products have demonstrated potent anti-tumor properties, thereby garnering considerable interest in their potential as anti-tumor drugs. This review compiles an overview of 242 recently discovered natural products, spanning the period from 2018 to the present. These natural products, which include 69 terpenoids, 42 alkaloids, 39 flavonoids, 21 steroids, 14 phenylpropanoids, 5 quinolines and 52 other compounds, are characterized by their respective chemical structures, anti-tumor activities, and mechanisms of action. By providing an essential reference and fresh insights, this review aims to support and inspire researchers engaged in the fields of natural products and anti-tumor drug discovery.
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Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Produtos Biológicos
/
Alcaloides
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Antineoplásicos
Idioma:
En
Ano de publicação:
2024
Tipo de documento:
Article