High-throughput digital quantification of Alzheimer disease pathology and associated infrastructure in large autopsy studies.

Kapasi, Alifiya; Poirier, Jennifer; Hedayat, Ahmad; Scherlek, Ashley; Mondal, Srabani; Wu, Tiffany; Gibbons, John; Barnes, Lisa L; Bennett, David A; Leurgans, Sue E; Schneider, Julie A

Kapasi, Alifiya; Poirier, Jennifer; Hedayat, Ahmad; Scherlek, Ashley; Mondal, Srabani; Wu, Tiffany; Gibbons, John; Barnes, Lisa L; Bennett, David A; Leurgans, Sue E; Schneider, Julie A.

Afiliação

Kapasi A; Rush Alzheimer's Disease Center, Rush University Medical Center, Chicago, Illinois, USA.
Poirier J; Department of Pathology, Rush University Medical Center, Chicago, Illinois, USA.
Hedayat A; Rush Alzheimer's Disease Center, Rush University Medical Center, Chicago, Illinois, USA.
Scherlek A; Department of Pathology, Washington University School of Medicine, St Louis, Missouri, USA.
Mondal S; Rush Alzheimer's Disease Center, Rush University Medical Center, Chicago, Illinois, USA.
Wu T; Rush Alzheimer's Disease Center, Rush University Medical Center, Chicago, Illinois, USA.
Gibbons J; Rush Alzheimer's Disease Center, Rush University Medical Center, Chicago, Illinois, USA.
Barnes LL; Rush Alzheimer's Disease Center, Rush University Medical Center, Chicago, Illinois, USA.
Bennett DA; Rush Alzheimer's Disease Center, Rush University Medical Center, Chicago, Illinois, USA.
Leurgans SE; Department of Neurological Sciences, Rush University Medical Center, Chicago, Illinois, USA.
Schneider JA; Rush Alzheimer's Disease Center, Rush University Medical Center, Chicago, Illinois, USA.

J Neuropathol Exp Neurol ; 82(12): 976-986, 2023 11 20.

Article em En | MEDLINE | ID: mdl-37944065

Assuntos

Doença de Alzheimer; Humanos; Doença de Alzheimer/diagnóstico por imagem; Autopsia; Peptídeos beta-Amiloides; Neuropatologia; Envelhecimento

Palavras-chave

Alzheimer disease; Digital pathology; Laboratory infrastructure; Microscopy; Neurofibrillary tangles; Neuropathology; ß-amyloid

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Doença de Alzheimer Limite: Humans Idioma: En Ano de publicação: 2023 Tipo de documento: Article

Texto completo

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XML

PubMed Links

Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Doença de Alzheimer Limite: Humans Idioma: En Ano de publicação: 2023 Tipo de documento: Article