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A transcriptomics-based drug repositioning approach to identify drugs with similar activities for the treatment of muscle pathologies in spinal muscular atrophy (SMA) models.
Hoolachan, Joseph M; McCallion, Eve; Sutton, Emma R; Çetin, Özge; Pacheco-Torres, Paloma; Dimitriadi, Maria; Sari, Suat; Miller, Gavin J; Okoh, Magnus; Walter, Lisa M; Claus, Peter; Wood, Matthew J A; Tonge, Daniel P; Bowerman, Melissa.
Afiliação
  • Hoolachan JM; School of Medicine, David Weatherall Building, Keele University, Staffordshire, ST5 5BG, United Kingdom.
  • McCallion E; School of Medicine, David Weatherall Building, Keele University, Staffordshire, ST5 5BG, United Kingdom.
  • Sutton ER; School of Medicine, David Weatherall Building, Keele University, Staffordshire, ST5 5BG, United Kingdom.
  • Çetin Ö; School of Medicine, David Weatherall Building, Keele University, Staffordshire, ST5 5BG, United Kingdom.
  • Pacheco-Torres P; School of Life and Medical Sciences, University of Hertfordshire, Hatfield, Hertfordshire, AL910 9AB, United Kingdom.
  • Dimitriadi M; School of Life and Medical Sciences, University of Hertfordshire, Hatfield, Hertfordshire, AL910 9AB, United Kingdom.
  • Sari S; Department of Pharmaceutical Chemistry, Hacettepe University, Ankara, 06100, Turkey.
  • Miller GJ; School of Chemical and Physical Sciences, Lennard-Jones Building, Keele University, Staffordshire, ST5 5BG, United Kingdom.
  • Okoh M; School of Chemical and Physical Sciences, Lennard-Jones Building, Keele University, Staffordshire, ST5 5BG, United Kingdom.
  • Walter LM; Centre for Glycoscience, Keele University, Staffordshire, ST5 5BG, United Kingdom.
  • Claus P; School of Medicine, David Weatherall Building, Keele University, Staffordshire, ST5 5BG, United Kingdom.
  • Wood MJA; SMATHERIA gGmbH - Non-Profit Biomedical Research Institute, Feodor-Lynen-Straße 31, 30625, Hannover, Germany.
  • Tonge DP; Centre of Systems Neuroscience (ZSN), Hannover Medical School, Bünteweg 2, 30559, Hannover, Germany.
  • Bowerman M; SMATHERIA gGmbH - Non-Profit Biomedical Research Institute, Feodor-Lynen-Straße 31, 30625, Hannover, Germany.
Hum Mol Genet ; 33(5): 400-425, 2024 Feb 18.
Article em En | MEDLINE | ID: mdl-37947217
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Atrofia Muscular Espinal / Reposicionamento de Medicamentos Limite: Animals Idioma: En Ano de publicação: 2024 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Atrofia Muscular Espinal / Reposicionamento de Medicamentos Limite: Animals Idioma: En Ano de publicação: 2024 Tipo de documento: Article