Prediction of CHO cell line stability using expression of DNA repair genes.

Cordova, Lauren T; Dahodwala, Hussain; Cooley, Rebecca; Lee, Kelvin H

Cordova, Lauren T; Dahodwala, Hussain; Cooley, Rebecca; Lee, Kelvin H.

Afiliação

Cordova LT; Department of Chemical and Biomolecular Engineering, University of Delaware, Newark, Delaware, USA.
Dahodwala H; Department of Chemical and Biomolecular Engineering, University of Delaware, Newark, Delaware, USA.
Cooley R; National Institute for Innovation in Manufacturing Biopharmaceuticals, Newark, Delaware, USA.
Lee KH; Pfizer, Inc, 875 Chesterfield Pkwy W, Chesterfield, Missouri, USA.

Biotechnol J ; 19(1): e2300425, 2024 Jan.

Article em En | MEDLINE | ID: mdl-37970758

Assuntos

Reparo do DNA; Cricetinae; Animais; Cricetulus; Células CHO; Células Clonais; Reparo do DNA/genética

Palavras-chave

CHO cells; CHO production instability; Lig4; Xrcc6; biomarkers; biopharmaceuticals; bioprocess development; bioprocess engineering

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Reparo do DNA Limite: Animals Idioma: En Ano de publicação: 2024 Tipo de documento: Article

Texto completo

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PubMed Links

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Reparo do DNA Limite: Animals Idioma: En Ano de publicação: 2024 Tipo de documento: Article