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Glutamine metabolism inhibition has dual immunomodulatory and antibacterial activities against Mycobacterium tuberculosis.
Parveen, Sadiya; Shen, Jessica; Lun, Shichun; Zhao, Liang; Alt, Jesse; Koleske, Benjamin; Leone, Robert D; Rais, Rana; Powell, Jonathan D; Murphy, John R; Slusher, Barbara S; Bishai, William R.
Afiliação
  • Parveen S; Center for Tuberculosis Research, Department of Medicine, Johns Hopkins School of Medicine, Baltimore, MD, USA.
  • Shen J; Center for Tuberculosis Research, Department of Medicine, Johns Hopkins School of Medicine, Baltimore, MD, USA.
  • Lun S; Center for Tuberculosis Research, Department of Medicine, Johns Hopkins School of Medicine, Baltimore, MD, USA.
  • Zhao L; Department of Oncology, Johns Hopkins School of Medicine, Baltimore, MD, USA.
  • Alt J; Johns Hopkins University, Baltimore, MD, USA.
  • Koleske B; Center for Tuberculosis Research, Department of Medicine, Johns Hopkins School of Medicine, Baltimore, MD, USA.
  • Leone RD; Department of Oncology, Johns Hopkins School of Medicine, Baltimore, MD, USA.
  • Rais R; The Bloomberg-Kimmel Institute for Cancer Immunotherapy, Johns Hopkins School of Medicine, Baltimore, MD, USA.
  • Powell JD; Johns Hopkins Drug Discovery, Johns Hopkins School of Medicine, Baltimore, MD, USA.
  • Murphy JR; Department of Neurology, Johns Hopkins School of Medicine, Baltimore, MD, USA.
  • Slusher BS; Department of Pharmacology and Molecular Sciences, Johns Hopkins School of Medicine, Baltimore, MD, USA.
  • Bishai WR; The Bloomberg-Kimmel Institute for Cancer Immunotherapy, Johns Hopkins School of Medicine, Baltimore, MD, USA.
Nat Commun ; 14(1): 7427, 2023 11 16.
Article em En | MEDLINE | ID: mdl-37973991

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Tuberculose / Mycobacterium tuberculosis Limite: Animals / Humans Idioma: En Ano de publicação: 2023 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Tuberculose / Mycobacterium tuberculosis Limite: Animals / Humans Idioma: En Ano de publicação: 2023 Tipo de documento: Article