The Rax homeoprotein in Müller glial cells is required for homeostasis maintenance of the postnatal mouse retina.

Yoshimoto, Takuya; Chaya, Taro; Varner, Leah R; Ando, Makoto; Tsujii, Toshinori; Motooka, Daisuke; Kimura, Kazuhiro; Furukawa, Takahisa

Yoshimoto, Takuya; Chaya, Taro; Varner, Leah R; Ando, Makoto; Tsujii, Toshinori; Motooka, Daisuke; Kimura, Kazuhiro; Furukawa, Takahisa.

Afiliação

Yoshimoto T; Laboratory for Molecular and Developmental Biology, Institute for Protein Research, Osaka University, Suita, Osaka, Japan; Department of Ophthalmology, Yamaguchi University Graduate School of Medicine, Yamaguchi University, Ube, Yamaguchi, Japan.
Chaya T; Laboratory for Molecular and Developmental Biology, Institute for Protein Research, Osaka University, Suita, Osaka, Japan.
Varner LR; Laboratory for Molecular and Developmental Biology, Institute for Protein Research, Osaka University, Suita, Osaka, Japan.
Ando M; Laboratory for Molecular and Developmental Biology, Institute for Protein Research, Osaka University, Suita, Osaka, Japan.
Tsujii T; Laboratory for Molecular and Developmental Biology, Institute for Protein Research, Osaka University, Suita, Osaka, Japan.
Motooka D; Genome Information Research Center, Research Institute for Microbial Diseases, Osaka University, Osaka, Japan.
Kimura K; Department of Ophthalmology, Yamaguchi University Graduate School of Medicine, Yamaguchi University, Ube, Yamaguchi, Japan.
Furukawa T; Laboratory for Molecular and Developmental Biology, Institute for Protein Research, Osaka University, Suita, Osaka, Japan. Electronic address: takahisa.furukawa@protein.osaka-u.ac.jp.

J Biol Chem ; 299(12): 105461, 2023 Dec.

Article em En | MEDLINE | ID: mdl-37977220

Assuntos

Células Ependimogliais; Proteínas do Olho; Proteínas de Homeodomínio; Homeostase; Retina; Fatores de Transcrição; Animais; Camundongos; Células Ependimogliais/metabolismo; Proteínas do Olho/genética; Proteínas do Olho/metabolismo; Gliose/genética; Gliose/metabolismo; Gliose/patologia; Proteínas de Homeodomínio/genética; Proteínas de Homeodomínio/metabolismo; Homeostase/genética; Retina/citologia; Retina/crescimento & desenvolvimento; Retina/metabolismo; Retina/patologia; RNA-Seq; Tamoxifeno/farmacologia; Fatores de Transcrição/genética; Fatores de Transcrição/metabolismo; Ativação Transcricional

Palavras-chave

Müller glial cell; homeostasis; inflammation; retina; transcription factor

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Retina / Fatores de Transcrição / Proteínas de Homeodomínio / Proteínas do Olho / Células Ependimogliais / Homeostase Limite: Animals Idioma: En Ano de publicação: 2023 Tipo de documento: Article

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