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Sequence-based prediction of the intrinsic solubility of peptides containing non-natural amino acids.
Oeller, Marc; Kang, Ryan J D; Bolt, Hannah L; Gomes Dos Santos, Ana L; Weinmann, Annika Langborg; Nikitidis, Antonios; Zlatoidsky, Pavol; Su, Wu; Czechtizky, Werngard; De Maria, Leonardo; Sormanni, Pietro; Vendruscolo, Michele.
Afiliação
  • Oeller M; Centre for Misfolding Diseases, Yusuf Hamied Department of Chemistry, University of Cambridge, Cambridge, UK.
  • Kang RJD; Proteomics and Signal Transduction, Max Planck Institute of Biochemistry, Martinsried, Germany.
  • Bolt HL; Centre for Misfolding Diseases, Yusuf Hamied Department of Chemistry, University of Cambridge, Cambridge, UK.
  • Gomes Dos Santos AL; Hit Discovery, Discovery Sciences, BioPharmaceuticals R&D, AstraZeneca, Cambridge, UK.
  • Weinmann AL; Advanced Drug Delivery, Pharmaceutical Sciences, BioPharmaceuticals R&D, AstraZeneca, Cambridge, United Kingdom.
  • Nikitidis A; Early Chemical Development, Pharmaceutical Sciences, BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden.
  • Zlatoidsky P; Medicinal Chemistry, Research and Early Development, Respiratory and Immunology, BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden.
  • Su W; Medicinal Chemistry, Research and Early Development, Respiratory and Immunology, BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden.
  • Czechtizky W; Medicinal Chemistry, Research and Early Development, Respiratory and Immunology, BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden.
  • De Maria L; Medicinal Chemistry, Research and Early Development, Respiratory and Immunology, BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden.
  • Sormanni P; Medicinal Chemistry, Research and Early Development, Respiratory and Immunology, BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden.
  • Vendruscolo M; Centre for Misfolding Diseases, Yusuf Hamied Department of Chemistry, University of Cambridge, Cambridge, UK. ps589@cam.ac.uk.
Nat Commun ; 14(1): 7475, 2023 11 17.
Article em En | MEDLINE | ID: mdl-37978172
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Peptídeos / Aminoácidos Idioma: En Ano de publicação: 2023 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Peptídeos / Aminoácidos Idioma: En Ano de publicação: 2023 Tipo de documento: Article