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A comprehensive review on anticancer evaluation techniques.
Sanjai, Chetana; Hakkimane, Sushruta S; Guru, Bharath Raja; Gaonkar, Santosh L.
Afiliação
  • Sanjai C; Department of Biotechnology, Manipal Institute of Technology Bengaluru, Manipal Academy of Higher Education, Manipal 576104, Karnataka, India.
  • Hakkimane SS; Department of Biotechnology, Manipal Institute of Technology Bengaluru, Manipal Academy of Higher Education, Manipal 576104, Karnataka, India. Electronic address: sushruta.s@manipal.edu.
  • Guru BR; Department of Biotechnology, Manipal Institute of Technology, Manipal Academy of Higher Education, Manipal 576104, Karnataka, India.
  • Gaonkar SL; Department of Chemistry, Manipal Institute of Technology, Manipal Academy of Higher Education, Manipal 576104, Karnataka, India. Electronic address: sl.gaonkar@manipal.edu.
Bioorg Chem ; 142: 106973, 2024 01.
Article em En | MEDLINE | ID: mdl-37984104
ABSTRACT
The development of effective anticancer strategies and the improvement of our understanding of cancer need analytical tools. Utilizing a variety of analytical approaches while investigating anti-cancer medicines gives us a thorough understanding of the traits and mechanisms concerned to cancer cells, which enables us to develop potent treatments to combat them. The importance of anticancer research may be attributed to various analytical techniques that contributes to the identification of therapeutic targets and the assessment of medication efficacy, which are crucial things in expanding our understanding of cancer biology. The study looks at methods that are often used in cancer research, including cell viability assays, clonogenic assay, flow cytometry, 2D electrophoresis, microarray, immunofluorescence, western blot caspase activation assay, bioinformatics, etc. The fundamentals, applications, and how each technique analytical advances our understanding of cancer are briefly reviewed.
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias Limite: Humans Idioma: En Ano de publicação: 2024 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias Limite: Humans Idioma: En Ano de publicação: 2024 Tipo de documento: Article