Matrine alleviates hypoxia-induced inflammation and pulmonary vascular remodelling via RPS5/NF-&#954;B signalling pathway.

Li, Mingxing; Ying, Miaofa; Gu, Shenglong; Zhou, Zheng; Zhao, Rui

Matrine alleviates hypoxia-induced inflammation and pulmonary vascular remodelling via RPS5/NF-κB signalling pathway.

Li, Mingxing; Ying, Miaofa; Gu, Shenglong; Zhou, Zheng; Zhao, Rui.

Afiliação

Li M; Department of Pharmacy, School of Medicine, Sir Run Run Shaw Hospital, Zhejiang University, Hangzhou, China.
Ying M; Department of Pharmacy, School of Medicine, Sir Run Run Shaw Hospital, Zhejiang University, Hangzhou, China.
Gu S; Department of Pharmacy, School of Medicine, Sir Run Run Shaw Hospital, Zhejiang University, Hangzhou, China.
Zhou Z; Department of Pharmacy, School of Medicine, Sir Run Run Shaw Hospital, Zhejiang University, Hangzhou, China.
Zhao R; Department of Pharmacy, School of Medicine, Sir Run Run Shaw Hospital, Zhejiang University, Hangzhou, China.

J Biochem Mol Toxicol ; 38(1): e23583, 2024 Jan.

Article em En | MEDLINE | ID: mdl-37986032

Assuntos

Hidralazina/análogos & derivados; Hipertensão Pulmonar; NF-kappa B; Ratos; Animais; NF-kappa B/metabolismo; Antígeno Nuclear de Célula em Proliferação/metabolismo; Matrinas; Hipertensão Pulmonar/tratamento farmacológico; Hipertensão Pulmonar/etiologia; Hipertensão Pulmonar/patologia; Remodelação Vascular; Proliferação de Células; Hipóxia/complicações; Hipóxia/metabolismo; Inflamação/metabolismo; Miócitos de Músculo Liso/metabolismo; Hidrazonas

Palavras-chave

PAH; RPS5/NF-κB signalling pathway; inflammation; matrine; vascular remodelling

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: NF-kappa B / Hidralazina / Hipertensão Pulmonar Limite: Animals Idioma: En Ano de publicação: 2024 Tipo de documento: Article

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