How important is the linearity assumption in a sample size calculation for a randomised controlled trial where treatment is anticipated to affect a rate of change?

Morgan, Katy E; White, Ian R; Frost, Chris

Morgan, Katy E; White, Ian R; Frost, Chris.

Afiliação

Morgan KE; Department of Medical Statistics, London School of Hygiene and Tropical Medicine, London, UK. katy.morgan@lshtm.ac.uk.
White IR; MRC Clinical Trials Unit at UCL, University College London, London, UK.
Frost C; Department of Medical Statistics, London School of Hygiene and Tropical Medicine, London, UK.

BMC Med Res Methodol ; 23(1): 274, 2023 11 21.

Article em En | MEDLINE | ID: mdl-37990159

Assuntos

Tamanho da Amostra; Humanos; Simulação por Computador

Palavras-chave

Linearity assumption; Model misspecification; Random slopes model; Randomised clinical trial; Sample size calculation

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Tamanho da Amostra Limite: Humans Idioma: En Ano de publicação: 2023 Tipo de documento: Article

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Tamanho da Amostra Limite: Humans Idioma: En Ano de publicação: 2023 Tipo de documento: Article