Allyl methyl disulfide (AMDS) prevents N,N-dimethyl formamide-induced liver damage by suppressing oxidative stress and NLRP3 inflammasome activation.

Li, Long-Xia; Wang, Lin; Wang, Shuo; Zhang, Xiu-Ning; Liu, Hong; Zhang, Yan-Jing; Wu, Chuan-Tao; Zhang, Cui-Li; Zeng, Tao

Li, Long-Xia; Wang, Lin; Wang, Shuo; Zhang, Xiu-Ning; Liu, Hong; Zhang, Yan-Jing; Wu, Chuan-Tao; Zhang, Cui-Li; Zeng, Tao.

Afiliação

Li LX; Institute of Toxicology, School of Public Health, Cheeloo College of Medicine, Shandong University, Jinan, Shandong, 250012, China.
Wang L; Institute of Toxicology, School of Public Health, Cheeloo College of Medicine, Shandong University, Jinan, Shandong, 250012, China.
Wang S; School of Pharmaceutical Sciences, Liaocheng University, Liaocheng, Shandong, 252059, China.
Zhang XN; Institute of Toxicology, School of Public Health, Cheeloo College of Medicine, Shandong University, Jinan, Shandong, 250012, China.
Liu H; Institute of Toxicology, School of Public Health, Cheeloo College of Medicine, Shandong University, Jinan, Shandong, 250012, China.
Zhang YJ; Institute of Toxicology, School of Public Health, Cheeloo College of Medicine, Shandong University, Jinan, Shandong, 250012, China.
Wu CT; The Animal Research Center, Shandong University, Jinan, Shandong, 250012, China.
Zhang CL; Institute of Toxicology, School of Public Health, Cheeloo College of Medicine, Shandong University, Jinan, Shandong, 250012, China. Electronic address: zcuilisdu@sdu.edu.cn.
Zeng T; Institute of Toxicology, School of Public Health, Cheeloo College of Medicine, Shandong University, Jinan, Shandong, 250012, China. Electronic address: zengtao@sdu.edu.cn.

Food Chem Toxicol ; 182: 114198, 2023 Dec.

Article em En | MEDLINE | ID: mdl-37995826

Assuntos

Inflamassomos; Hepatopatias; Humanos; Camundongos; Animais; Inflamassomos/metabolismo; Proteína 3 que Contém Domínio de Pirina da Família NLR/genética; Proteína 3 que Contém Domínio de Pirina da Família NLR/metabolismo; NF-kappa B/metabolismo; Dimetilformamida/toxicidade; Dimetilformamida/metabolismo; Hepatopatias/metabolismo; Estresse Oxidativo; Fígado; Glutationa/metabolismo

Palavras-chave

Allyl methyl disulfide; Environmental pollutant; Liver injury; N,N-dimethylformamide; NLRP3 inflammasome

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Inflamassomos / Hepatopatias Limite: Animals / Humans Idioma: En Ano de publicação: 2023 Tipo de documento: Article

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