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The helminth TGF-ß mimic TGM4 is a modular ligand that binds CD44, CD49d and TGF-ß receptors to preferentially target myeloid cells.
Singh, Shashi P; Smyth, Danielle J; Cunningham, Kyle; Mukundan, Ananya; Byeon, Chang-Hyeock; Hinck, Cynthia S; White, Madeleine P J; Ciancia, Claire; Wosowska, Natalia; Sanders, Anna; Jin, Regina; Lilla, Sergio; Zanivan, Sara; Schoenherr, Christina; Inman, Gareth; van Dinther, Maarten; Ten Dijke, Peter; Hinck, Andrew P; Maizels, Rick M.
Afiliação
  • Singh SP; Wellcome Centre of Integrative Parasitology, School of Infection and Immunity, University of Glasgow, G12 8TA, UK.
  • Smyth DJ; Wellcome Centre of Integrative Parasitology, School of Infection and Immunity, University of Glasgow, G12 8TA, UK.
  • Cunningham K; Wellcome Centre of Integrative Parasitology, School of Infection and Immunity, University of Glasgow, G12 8TA, UK.
  • Mukundan A; Department of Structural Biology, University of Pittsburgh, USA.
  • Byeon CH; Department of Structural Biology, University of Pittsburgh, USA.
  • Hinck CS; Department of Structural Biology, University of Pittsburgh, USA.
  • White MPJ; Wellcome Centre of Integrative Parasitology, School of Infection and Immunity, University of Glasgow, G12 8TA, UK.
  • Ciancia C; Wellcome Centre of Integrative Parasitology, School of Infection and Immunity, University of Glasgow, G12 8TA, UK.
  • Wosowska N; Wellcome Centre of Integrative Parasitology, School of Infection and Immunity, University of Glasgow, G12 8TA, UK.
  • Sanders A; Wellcome Centre of Integrative Parasitology, School of Infection and Immunity, University of Glasgow, G12 8TA, UK.
  • Jin R; Wellcome Centre of Integrative Parasitology, School of Infection and Immunity, University of Glasgow, G12 8TA, UK.
  • Lilla S; Cancer Research UK Scotland Institute, Glasgow, G61 1BD, UK.
  • Zanivan S; Cancer Research UK Scotland Institute, Glasgow, G61 1BD, UK.
  • Schoenherr C; Cancer Research UK Scotland Institute, Glasgow, G61 1BD, UK.
  • Inman G; Cancer Research UK Scotland Institute, Glasgow, G61 1BD, UK.
  • van Dinther M; Oncode Institute and Department of Cell and Chemical Biology, University of Leiden, The Netherlands.
  • Ten Dijke P; Oncode Institute and Department of Cell and Chemical Biology, University of Leiden, The Netherlands.
  • Hinck AP; Department of Structural Biology, University of Pittsburgh, USA.
  • Maizels RM; Wellcome Centre of Integrative Parasitology, School of Infection and Immunity, University of Glasgow, G12 8TA, UK.
bioRxiv ; 2023 Nov 15.
Article em En | MEDLINE | ID: mdl-38014296
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Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2023 Tipo de documento: Article
Texto completo
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PubMed Links
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Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2023 Tipo de documento: Article