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Synthetic CRISPR/dCas9-KRAB system driven by specific PSA promoter suppresses malignant biological behavior of prostate cancer cells through negative feedback inhibition of PSA expression.
Yang, Yi; Mei, Hongbing; Han, Xiaohong; Zhang, Xintao; Cheng, Jianli; Zhang, Zhongfu; Wang, Han; Xu, Haixia.
Afiliação
  • Yang Y; Department of Urology, The First Affiliated Hospital of Shenzhen University, Shenzhen Second People's Hospital, Shenzhen, China.
  • Mei H; Department of Urology, The First Affiliated Hospital of Shenzhen University, Shenzhen Second People's Hospital, Shenzhen, China.
  • Han X; Department of Urology, The First Affiliated Hospital of Shenzhen University, Shenzhen Second People's Hospital, Shenzhen, China.
  • Zhang X; Department of Urology, The First Affiliated Hospital of Shenzhen University, Shenzhen Second People's Hospital, Shenzhen, China.
  • Cheng J; Department of Urology, The First Affiliated Hospital of Shenzhen University, Shenzhen Second People's Hospital, Shenzhen, China.
  • Zhang Z; Department of Urology, The First Affiliated Hospital of Shenzhen University, Shenzhen Second People's Hospital, Shenzhen, China.
  • Wang H; Department of Urology, The First Affiliated Hospital of Shenzhen University, Shenzhen Second People's Hospital, Shenzhen, China.
  • Xu H; Department of Medical Oncology, The First Affiliated Hospital of Shenzhen University, Shenzhen Second People's Hospital, Shenzhen, China. 182199558@qq.com.
Cell Mol Biol Lett ; 28(1): 96, 2023 Nov 28.
Article em En | MEDLINE | ID: mdl-38017385
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias da Próstata / Repetições Palindrômicas Curtas Agrupadas e Regularmente Espaçadas Limite: Humans / Male Idioma: En Ano de publicação: 2023 Tipo de documento: Article
Texto completo
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XML
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias da Próstata / Repetições Palindrômicas Curtas Agrupadas e Regularmente Espaçadas Limite: Humans / Male Idioma: En Ano de publicação: 2023 Tipo de documento: Article