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A T cell receptor ß chain-directed antibody fusion molecule activates and expands subsets of T cells to promote antitumor activity.
Hsu, Jonathan; Donahue, Renee N; Katragadda, Madan; Lowry, Jessica; Huang, Wei; Srinivasan, Karunya; Guntas, Gurkan; Tang, Jian; Servattalab, Roya; Moisan, Jacques; Tsai, Yo-Ting; Stoop, Allart; Palakurthi, Sangeetha; Chopra, Raj; Liu, Ke; Wherry, E John; Su, Zhen; Gulley, James L; Bayliffe, Andrew; Schlom, Jeffrey.
Afiliação
  • Hsu J; Marengo Therapeutics, Cambridge, MA 02139, USA.
  • Donahue RN; Center for Immuno-Oncology, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, MD 20892, USA.
  • Katragadda M; Marengo Therapeutics, Cambridge, MA 02139, USA.
  • Lowry J; Marengo Therapeutics, Cambridge, MA 02139, USA.
  • Huang W; Marengo Therapeutics, Cambridge, MA 02139, USA.
  • Srinivasan K; Marengo Therapeutics, Cambridge, MA 02139, USA.
  • Guntas G; Marengo Therapeutics, Cambridge, MA 02139, USA.
  • Tang J; Marengo Therapeutics, Cambridge, MA 02139, USA.
  • Servattalab R; Marengo Therapeutics, Cambridge, MA 02139, USA.
  • Moisan J; Marengo Therapeutics, Cambridge, MA 02139, USA.
  • Tsai YT; Center for Immuno-Oncology, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, MD 20892, USA.
  • Stoop A; Marengo Therapeutics, Cambridge, MA 02139, USA.
  • Palakurthi S; Marengo Therapeutics, Cambridge, MA 02139, USA.
  • Chopra R; Marengo Therapeutics, Cambridge, MA 02139, USA.
  • Liu K; Marengo Therapeutics, Cambridge, MA 02139, USA.
  • Wherry EJ; Department of Systems Pharmacology and Translational Therapeutics, University of Pennsylvania, Philadelphia, PA 19104, USA.
  • Su Z; Institute for Immunology, University of Pennsylvania, Philadelphia, PA 19104, USA.
  • Gulley JL; Marengo Therapeutics, Cambridge, MA 02139, USA.
  • Bayliffe A; Center for Immuno-Oncology, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, MD 20892, USA.
  • Schlom J; Marengo Therapeutics, Cambridge, MA 02139, USA.
Sci Transl Med ; 15(724): eadi0258, 2023 11 29.
Article em En | MEDLINE | ID: mdl-38019931
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Receptores de Antígenos de Linfócitos T alfa-beta / Neoplasias Limite: Animals / Humans Idioma: En Ano de publicação: 2023 Tipo de documento: Article
Texto completo
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Receptores de Antígenos de Linfócitos T alfa-beta / Neoplasias Limite: Animals / Humans Idioma: En Ano de publicação: 2023 Tipo de documento: Article