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Bacteriophage-based approach for treatment of urinary tract infections: a quick outlook.
Grygorcewicz, Bartlomiej; Glizniewicz, Marta; Jablonska, Joanna; Augustyniak, Adrian; Olszewska, Patrycja; Wojciuk, Bartosz; Milek, Dominika; Serwin, Natalia; Czajkowski, Artur; Cecerska-Heryc, Elzbieta; Rakoczy, Rafal; Cymbaluk-Ploska, Aneta.
Afiliação
  • Grygorcewicz B; Faculty of Pharmacy, Medical Biotechnology and Laboratory Medicine, Pomeranian Medical University in Szczecin, Szczecin, Poland.
  • Glizniewicz M; Department of Chemical and Process Engineering, Faculty of Chemical Technology and Engineering, West Pomeranian University of Technology, Szczecin, Szczecin, Poland.
  • Jablonska J; Faculty of Pharmacy, Medical Biotechnology and Laboratory Medicine, Pomeranian Medical University in Szczecin, Szczecin, Poland.
  • Augustyniak A; Department of Chemical and Process Engineering, Faculty of Chemical Technology and Engineering, West Pomeranian University of Technology, Szczecin, Szczecin, Poland.
  • Olszewska P; Department of Chemical and Process Engineering, Faculty of Chemical Technology and Engineering, West Pomeranian University of Technology, Szczecin, Szczecin, Poland.
  • Wojciuk B; Chair of Building Materials and Construction Chemistry, Technische Universität Berlin, Germany, Berlin, Germany.
  • Milek D; Institute of Biology, University of Szczecin, Szczecin, Poland.
  • Serwin N; Faculty of Pharmacy, Medical Biotechnology and Laboratory Medicine, Pomeranian Medical University in Szczecin, Szczecin, Poland.
  • Czajkowski A; Department of Immunology Diagnostics, Chair of Microbiology, Immunology and Laboratory Medicine, Pomeranian Medical University in Szczecin, Szczecin, Poland.
  • Cecerska-Heryc E; Faculty of Pharmacy, Medical Biotechnology and Laboratory Medicine, Pomeranian Medical University in Szczecin, Szczecin, Poland.
  • Rakoczy R; Faculty of Pharmacy, Medical Biotechnology and Laboratory Medicine, Pomeranian Medical University in Szczecin, Szczecin, Poland.
  • Cymbaluk-Ploska A; Faculty of Pharmacy, Medical Biotechnology and Laboratory Medicine, Pomeranian Medical University in Szczecin, Szczecin, Poland.
APMIS ; 132(2): 81-93, 2024 Feb.
Article em En | MEDLINE | ID: mdl-38031200
ABSTRACT
Urinary tract infections (UTIs) are among the most common bacterial infections affecting millions worldwide. The increasing emergence of antibiotic-resistant bacteria has become a serious concern in managing UTIs. Therefore, there is a growing interest in using bacteriophages as an alternative or adjunct therapy for UTIs. Bacteriophages are viruses that infect and kill bacteria, making them a promising tool for treating UTIs caused by antibiotic-resistant bacteria. This article provides a quick outlook on using bacteriophages to treat UTIs. We summarize the current understanding of the biology of bacteriophages, the challenges associated with developing phage-based therapies, and the promising results of several case reports and clinical trials. We also highlight the potential of phage therapy as a valuable tool in the fight against antibiotic-resistant UTIs. This quick outlook on a bacteriophage-based approach for treating UTIs offers a timely and informative summary of the current research in this field.
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Infecções Bacterianas / Bacteriófagos / Infecções Urinárias Limite: Humans Idioma: En Ano de publicação: 2024 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Infecções Bacterianas / Bacteriófagos / Infecções Urinárias Limite: Humans Idioma: En Ano de publicação: 2024 Tipo de documento: Article