Genetic Profiling Uncovers Genome-Wide Loss of Heterozygosity and Provides Insight into Mechanisms of Sarcomatoid Transformation in Chromophobe Renal Cell Carcinoma.

Collins, Katrina; Acosta, Andres M; Siegmund, Stephanie E; Cheng, Liang; Hirsch, Michelle S; Idrees, Muhammad T

Collins, Katrina; Acosta, Andres M; Siegmund, Stephanie E; Cheng, Liang; Hirsch, Michelle S; Idrees, Muhammad T.

Afiliação

Collins K; Department of Pathology, Indiana University School of Medicine, Indianapolis, Indiana. Electronic address: katcoll@iu.edu.
Acosta AM; Department of Pathology, Indiana University School of Medicine, Indianapolis, Indiana.
Siegmund SE; Department of Pathology, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts.
Cheng L; Department of Pathology, Warren Alpert Medical School of Brown University, Lifespan Academic Medical Center, Providence, Rhode Island.
Hirsch MS; Department of Pathology, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts.
Idrees MT; Department of Pathology, Indiana University School of Medicine, Indianapolis, Indiana.

Mod Pathol ; 37(2): 100396, 2024 Feb.

Article em En | MEDLINE | ID: mdl-38043790

Assuntos

Carcinoma de Células Renais; Neoplasias Renais; Sarcoma; Humanos; Carcinoma de Células Renais/genética; Carcinoma de Células Renais/patologia; Neoplasias Renais/genética; Neoplasias Renais/patologia; Duplicação Cromossômica; Sarcoma/genética; Aberrações Cromossômicas; Perda de Heterozigosidade; Nucleotídeos

Palavras-chave

chromophobe; genomic; p53; profiling; renal cell carcinoma; sarcomatoid; sequencing

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Sarcoma / Carcinoma de Células Renais / Neoplasias Renais Limite: Humans Idioma: En Ano de publicação: 2024 Tipo de documento: Article

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