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Beta-blocker management in patients admitted for acute heart failure and reduced ejection fraction: a review and expert consensus opinion.
Schurtz, Guillaume; Mewton, Nathan; Lemesle, Gilles; Delmas, Clément; Levy, Bruno; Puymirat, Etienne; Aissaoui, Nadia; Bauer, Fabrice; Gerbaud, Edouard; Henry, Patrick; Bonello, Laurent; Bochaton, Thomas; Bonnefoy, Eric; Roubille, François; Lamblin, Nicolas.
Afiliação
  • Schurtz G; USIC et Centre Hémodynamique, Institut Coeur Poumon, Centre Hospitalier Universitaire de Lille, Lille, France.
  • Mewton N; Hôpital Cardio-Vasculaire Louis Pradel. Filière Insuffisance Cardiaque, Centre D'Investigation Clinique, INSERM 1407. Unité CarMeN, INSERM 1060, Hospices Civils de Lyon, Université Claude Bernard Lyon 1, Lyon, France.
  • Lemesle G; USIC et Centre Hémodynamique, Institut Coeur Poumon, Centre Hospitalier Universitaire de Lille, Lille, France.
  • Delmas C; Institut Pasteur de Lille, Unité INSERM UMR1011, Lille, France.
  • Levy B; Faculté de Médecine de l'Université de Lille, Lille, France.
  • Puymirat E; FACT (French Alliance for Cardiovascular Trials), Paris, France.
  • Aissaoui N; Intensive Cardiac Care Unit, Rangueil University Hospital, Toulouse, France.
  • Bauer F; Service de Réanimation Médicale Brabois, CHRU Nancy, Pôle Cardio-Médico-Chirurgical, Vandoeuvre-les-Nancy, INSERM U1116, Faculté de Médecine, Vandoeuvre-les-Nancy, Université de Lorraine, Nancy, France.
  • Gerbaud E; Department of Cardiology, Assistance Publique des Hôpitaux de Paris, Paris, France.
  • Henry P; Médecine Intensive Réanimation, Cochin, AfterROSC, Assistance Publique-Hôpitaux de Paris (AP-HP), Université Paris Cité, Paris, France.
  • Bonello L; Heart Failure Network, Advanced Heart Failure Clinic and Pulmonary Hypertension Department, Cardiac Surgery Department, INSERM U1096, Rouen University Teaching Hospital, Rouen, France.
  • Bochaton T; Cardiology Intensive Care Unit and Interventional Cardiology, Hôpital Cardiologique du Haut-Lévêque, Pessac, France.
  • Bonnefoy E; Bordeaux Cardio-Thoracic Research Centre, INSERM U1045, Bordeaux University, Bordeaux, France.
  • Roubille F; Department of Cardiology, Assistance Publique-Hôpitaux de Paris, INSERM U942, University of Paris, Paris, France.
  • Lamblin N; Cardiology Department, APHM, Mediterranean Association for Research and Studies in Cardiology (MARS Cardio), Centre for CardioVascular and Nutrition Research (C2VN), INSERM 1263, INRA 1260, Aix-Marseille Univ, Marseille, France.
Front Cardiovasc Med ; 10: 1263482, 2023.
Article em En | MEDLINE | ID: mdl-38050613
ABSTRACT
The role of the beta-adrenergic signaling pathway in heart failure (HF) is pivotal. Early blockade of this pathway with beta-blocker (BB) therapy is recommended as the first-line medication for patients with HF and reduced ejection fraction (HFrEF). Conversely, in patients with severe acute HF (AHF), including those with resolved cardiogenic shock (CS), BB initiation can be hazardous. There are very few data on the management of BB in these situations. The present expert consensus aims to review all published data on the use of BB in patients with severe decompensated AHF, with or without hemodynamic compromise, and proposes an expert-recommended practical algorithm for the prescription and monitoring of BB therapy in critical settings.
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Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2023 Tipo de documento: Article
Texto completo
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XML
PubMed Links
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Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2023 Tipo de documento: Article