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Enhancement and Comparison of (Ceftazidime-)Avibactam Plus Aztreonam Susceptibility Tests for Stenotrophomonas maltophilia in Clinical Diagnostics.
Vlaspolder, Gro L; Hughes, Laura A; Huis In 't Veld, Robert A G; Kampinga, Greetje A; Bathoorn, Erik.
Afiliação
  • Vlaspolder GL; Department of Medical Microbiology and Infection Prevention, University Medical Centre Groningen, University of Groningen, Hanzeplein 1, PO Box 30001, 9700RB, Groningen, The Netherlands.
  • Hughes LA; Department of Medical Microbiology and Infection Prevention, University Medical Centre Groningen, University of Groningen, Hanzeplein 1, PO Box 30001, 9700RB, Groningen, The Netherlands.
  • Huis In 't Veld RAG; Department of Medical Microbiology and Infection Prevention, University Medical Centre Groningen, University of Groningen, Hanzeplein 1, PO Box 30001, 9700RB, Groningen, The Netherlands.
  • Kampinga GA; Department of Medical Microbiology and Infection Prevention, University Medical Centre Groningen, University of Groningen, Hanzeplein 1, PO Box 30001, 9700RB, Groningen, The Netherlands.
  • Bathoorn E; Department of Medical Microbiology and Infection Prevention, University Medical Centre Groningen, University of Groningen, Hanzeplein 1, PO Box 30001, 9700RB, Groningen, The Netherlands. d.bathoorn@umcg.nl.
Curr Microbiol ; 81(1): 28, 2023 Dec 05.
Article em En | MEDLINE | ID: mdl-38051338
ABSTRACT
Stenotrophomonas maltophilia is naturally resistant to many antimicrobials. We evaluated the in vitro activity and reproducibility of two different super-position methods of aztreonam in combination with ceftazidime-avibactam for S. maltophilia and compared these results with the recently available aztreonam-avibactam gradient strip. We recommend an improved super-position method that avoids the possible risk of handling a contaminated aztreonam strip. In addition, we report that the cefazidime-avibactam and aztreonam super-position method showed increased in vitro activity in comparison with aztreonam-avibactam indicating activity of the ceftazidime component in vitro.
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Aztreonam / Stenotrophomonas maltophilia Idioma: En Ano de publicação: 2023 Tipo de documento: Article
Texto completo
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XML
PubMed Links
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Aztreonam / Stenotrophomonas maltophilia Idioma: En Ano de publicação: 2023 Tipo de documento: Article