Melanogrit potentiates melanogenesis by escalating cellular tyrosinase activity and MITF levels via pERK inhibition.

Balkrishna, Acharya; Lochab, Savita; Verma, Sudeep; Srivastava, Jyotish; Dev, Rishabh; Varshney, Anurag

Balkrishna, Acharya; Lochab, Savita; Verma, Sudeep; Srivastava, Jyotish; Dev, Rishabh; Varshney, Anurag.

Afiliação

Balkrishna A; Drug Discovery and Development Division, Patanjali Research Foundation, NH-58, Haridwar 249405, Uttarakhand, India.
Lochab S; Department of Allied and Applied Sciences, University of Patanjali, Patanjali Yog Peeth, Roorkee-Haridwar Road, Haridwar 249405, Uttarakhand, India.
Verma S; Patanjali Yog Peeth (UK) Trust, 40 Lambhill Street, Kinning Park, Glasgow G41 1AU, U.K.
Srivastava J; Vedic Acharya Samaj Foundation, Inc. NFP, 21725 CR 33, Groveland, FL 34736, U.S.A.
Dev R; Drug Discovery and Development Division, Patanjali Research Foundation, NH-58, Haridwar 249405, Uttarakhand, India.
Varshney A; Drug Discovery and Development Division, Patanjali Research Foundation, NH-58, Haridwar 249405, Uttarakhand, India.

Biosci Rep ; 44(1)2024 Jan 31.

Article em En | MEDLINE | ID: mdl-38054639

Assuntos

Monofenol Mono-Oxigenase; Vitiligo; Animais; Humanos; Camundongos; Linhagem Celular Tumoral; Melanócitos/metabolismo; Melanogênese; Fator de Transcrição Associado à Microftalmia/genética; Fator de Transcrição Associado à Microftalmia/metabolismo; Monofenol Mono-Oxigenase/genética; Monofenol Mono-Oxigenase/metabolismo; Monofenol Mono-Oxigenase/farmacologia; Transdução de Sinais; Vitiligo/metabolismo

Palavras-chave

B16F10; MITF; Melanogenesis; cellular tyrosinase activity; keratinocytes-melanocyte co-culture

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Vitiligo / Monofenol Mono-Oxigenase Limite: Animals / Humans Idioma: En Ano de publicação: 2024 Tipo de documento: Article

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