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Hepatocyte CHRNA4 mediates the MASH-promotive effects of immune cell-produced acetylcholine and smoking exposure in mice and humans.
Pan, Chuyue; Liu, Jun; Gao, Yingsheng; Yang, Maohui; Hu, Haiyang; Liu, Chang; Qian, Minyi; Yuan, Hai-Yang; Yang, Song; Zheng, Ming-Hua; Wang, Lirui.
Afiliação
  • Pan C; Institute of Modern Biology, Nanjing University, Nanjing 210008, China; School of Basic Medicine and Clinical Pharmacy, China Pharmaceutical University, Nanjing, Jiang Su 211198, China.
  • Liu J; School of Basic Medicine and Clinical Pharmacy, China Pharmaceutical University, Nanjing, Jiang Su 211198, China.
  • Gao Y; School of Basic Medicine and Clinical Pharmacy, China Pharmaceutical University, Nanjing, Jiang Su 211198, China.
  • Yang M; Institute of Modern Biology, Nanjing University, Nanjing 210008, China.
  • Hu H; School of Life Science and Technology, China Pharmaceutical University, Nanjing, Jiang Su 211198, China.
  • Liu C; Institute of Modern Biology, Nanjing University, Nanjing 210008, China.
  • Qian M; School of Basic Medicine and Clinical Pharmacy, China Pharmaceutical University, Nanjing, Jiang Su 211198, China.
  • Yuan HY; MAFLD Research Center, Department of Hepatology, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, China; Key Laboratory of Diagnosis and Treatment for The Development of Chronic Liver Disease in Zhejiang Province, Wenzhou, China.
  • Yang S; Department of Hepatology, Beijing Ditan Hospital, Capital Medical University, 8 Jingshun East Street, Chaoyang District, Beijing 100015, China. Electronic address: sduyangsong@163.com.
  • Zheng MH; MAFLD Research Center, Department of Hepatology, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, China; Key Laboratory of Diagnosis and Treatment for The Development of Chronic Liver Disease in Zhejiang Province, Wenzhou, China. Electronic address: zhengmh@wmu.edu.cn.
  • Wang L; Institute of Modern Biology, Nanjing University, Nanjing 210008, China. Electronic address: wanglirui@nju.edu.cn.
Cell Metab ; 35(12): 2231-2249.e7, 2023 12 05.
Article em En | MEDLINE | ID: mdl-38056431
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Acetilcolina / Fígado Gorduroso Limite: Animals / Humans Idioma: En Ano de publicação: 2023 Tipo de documento: Article
Texto completo
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PubMed Links
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Acetilcolina / Fígado Gorduroso Limite: Animals / Humans Idioma: En Ano de publicação: 2023 Tipo de documento: Article