The Relationship between Age at Initiation of Regular Drinking of Alcohol and Viral Suppression Status, and Depression Symptoms Among People Living with HIV in South-Western Uganda.
AIDS Behav
; 28(4): 1415-1422, 2024 Apr.
Article
em En
| MEDLINE
| ID: mdl-38060110
ABSTRACT
Alcohol use is an important factor in achieving and maintaining viral suppression and optimal mental health among persons with HIV (PWH), however, the effect of age at first regular drinking on viral suppression and depression remains poorly understood. Here, using secondary data from the Alcohol Drinkers' Exposure to Preventive Therapy for Tuberculosis (ADEPT-T) study, we used logistic regression analyses to explore whether there is an association between age at first regular drinking and viral suppression (< 40 copies/ml), or presence of depressive symptoms (Center for Epidemiologic Studies Depression, CES-D ≥ 16) among 262 PWH. The median age at first regular drinking was 20.5 years (IQR 10), with high proportions starting under age 12 (12.2%) and as teens (13.4%). The majority had an undetectable viral load (91.7%) and 11% had symptoms of probable depression. We found no significant association between age at first regular drinking and viral suppression (i.e., child (aOR = 0.76 95%CI 0.18, 3.26), adolescent (aOR = 0.74 95%CI 0.18, 2.97) and young adult (aOR = 1.27 95%CI 0.40, 3.97)) nor with depressive symptoms (i.e., child (aOR = 0.72 95%CI 0.19, 2.83), adolescent (aOR = 0.59 95%CI 0.14, 2.50) and young adult (aOR = 0.57 95%CI 0.22, 1.53)). Age at first regular drinking among PWH did not appear to be associated with either viral suppression or the presence of depressive symptoms, suggesting interventions may best be focused on the harmful effects of current alcohol use.
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Texto completo:
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Base de dados:
MEDLINE
Assunto principal:
Infecções por HIV
Limite:
Adolescent
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Adult
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Child
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Humans
País como assunto:
Africa
Idioma:
En
Ano de publicação:
2024
Tipo de documento:
Article