The in-vitro chemosensitivity of three cell lines derived from the VM/DK spontaneous murine astrocytoma.
J Neurol Neurosurg Psychiatry
; 49(12): 1361-6, 1986 Dec.
Article
em En
| MEDLINE
| ID: mdl-3806112
ABSTRACT
Three cell lines, VM/Dk P497 P540 and P560 derived from the VM spontaneous murine astrocytoma have previously been fully characterised and found to differ in their degree of astrocytic differentiation. The in vitro chemosensitivity of the three lines has been investigated using the 35S-methionine uptake assay. Differential chemosensitivity was found to exist between the cell lines. The pattern of chemosensitivity in relation to astrocytic differentiation was complex but the least differentiated cell line, P497, tended to be the least chemosensitive.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Astrocitoma
/
Antineoplásicos
Limite:
Animals
Idioma:
En
Ano de publicação:
1986
Tipo de documento:
Article