Generation of antigen-specific mature T cells from RAG1-/-RAG2-/-B2M-/- stem cells by engineering their microenvironment.

Chang, Patrick C; Yuan, Xuegang; Zampieri, Alexandre; Towns, Chloe; Yoo, Sang Pil; Engstrom, Claire; Tsai, Steven; Robles, Christopher R; Zhu, Yuhua; Lopez, Shawn; Montel-Hagen, Amelie; Seet, Christopher S; Crooks, Gay M

Generation of antigen-specific mature T cells from RAG1^-/-RAG2^-/-B2M^-/- stem cells by engineering their microenvironment.

Chang, Patrick C; Yuan, Xuegang; Zampieri, Alexandre; Towns, Chloe; Yoo, Sang Pil; Engstrom, Claire; Tsai, Steven; Robles, Christopher R; Zhu, Yuhua; Lopez, Shawn; Montel-Hagen, Amelie; Seet, Christopher S; Crooks, Gay M.

Afiliação

Chang PC; Molecular Biology Interdepartmental Program, University of California, Los Angeles (UCLA), Los Angeles, CA, USA.
Yuan X; Department of Pathology and Laboratory Medicine, David Geffen School of Medicine, UCLA, Los Angeles, CA, USA.
Zampieri A; Department of Pathology and Laboratory Medicine, David Geffen School of Medicine, UCLA, Los Angeles, CA, USA.
Towns C; Department of Pathology and Laboratory Medicine, David Geffen School of Medicine, UCLA, Los Angeles, CA, USA.
Yoo SP; Department of Pathology and Laboratory Medicine, David Geffen School of Medicine, UCLA, Los Angeles, CA, USA.
Engstrom C; Molecular Biology Interdepartmental Program, University of California, Los Angeles (UCLA), Los Angeles, CA, USA.
Tsai S; Department of Pathology and Laboratory Medicine, David Geffen School of Medicine, UCLA, Los Angeles, CA, USA.
Robles CR; Department of Pathology and Laboratory Medicine, David Geffen School of Medicine, UCLA, Los Angeles, CA, USA.
Zhu Y; Division of Hematology-Oncology, Department of Medicine, David Geffen School of Medicine, UCLA, Los Angeles, CA, USA.
Lopez S; Department of Computational Medicine, UCLA, Los Angeles, CA, USA.
Montel-Hagen A; Department of Pathology and Laboratory Medicine, David Geffen School of Medicine, UCLA, Los Angeles, CA, USA.
Seet CS; Department of Pathology and Laboratory Medicine, David Geffen School of Medicine, UCLA, Los Angeles, CA, USA.
Crooks GM; Department of Pathology and Laboratory Medicine, David Geffen School of Medicine, UCLA, Los Angeles, CA, USA.

Nat Biomed Eng ; 2023 Dec 07.

Article em En | MEDLINE | ID: mdl-38062131

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Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2023 Tipo de documento: Article

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Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2023 Tipo de documento: Article